Gastrointestinal Kaposi Sarcoma Involving Stomach and Colon: Diagnostic Pitfall for Pathologists with Expression of CD117

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dc.authoridKaradag Soylu, Nese/0000-0002-6303-5484
dc.authoridTOPRAK, SERHAT/0000-0003-4136-0523
dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authorwosidKaradag Soylu, Nese/ABH-9544-2020
dc.authorwosidTOPRAK, SERHAT/AAD-7854-2021
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.contributor.authorBozdag, Zehra
dc.contributor.authorToprak, Serhat
dc.contributor.authorKaradag, Nese
dc.contributor.authorAkbulut, Sami
dc.date.accessioned2024-08-04T20:51:36Z
dc.date.available2024-08-04T20:51:36Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractKaposi sarcoma (KS) is a low-grade vascular tumor caused by human herpes virus type 8 (HHV8). Gastrointestinal involvement of KS is rare and most commonly clinically silent. Gastrointestinal KS may mimic gastrointestinal stromal tumors (GISTs) histologically as the tumor formed by morphologically spindle-shaped cells, which is mostly located in the mucosa and submucosa. In the present study, we describe a case of Kaposi sarcoma that was first diagnosed in the gastrointestinal tract of a 73-year-old female patient who presented to the clinic with nausea and diarrhea. Immunohistochemical staining showed cytoplasmic CD117 expression both in stomach and colon biopsies. Although involvement of KS is rarely seen in the gastrointestinal tract (GIT), the differential diagnosis of low-grade spindle cell lesions without significant pleomorphism, KS should definitely be considered, and it should be known that CD117 positivity is also present in these neoplasms.en_US
dc.identifier.doi10.1007/s12029-021-00785-w
dc.identifier.endpage293en_US
dc.identifier.issn1941-6628
dc.identifier.issn1941-6636
dc.identifier.issue1en_US
dc.identifier.pmid35060100en_US
dc.identifier.scopus2-s2.0-85123240127en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage290en_US
dc.identifier.urihttps://doi.org/10.1007/s12029-021-00785-w
dc.identifier.urihttps://hdl.handle.net/11616/100424
dc.identifier.volume54en_US
dc.identifier.wosWOS:000744858700001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Gastrointestinal Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectKaposi sarcomaen_US
dc.subjectGastrointestinal tract involvementen_US
dc.subjectStomachen_US
dc.subjectColonen_US
dc.titleGastrointestinal Kaposi Sarcoma Involving Stomach and Colon: Diagnostic Pitfall for Pathologists with Expression of CD117en_US
dc.typeArticleen_US

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