Quantification of nitric oxide and cytokines in rabbit aqueous humor after neodymium:YAG laser capsulotomy

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dc.authoridGündüz, Abuzer/0000-0003-1752-6810
dc.authoridTürköz, Yusuf/0000-0001-5401-0720;
dc.authorwosidGündüz, Abuzer/HLH-2417-2023
dc.authorwosidTürköz, Yusuf/ABG-7931-2020
dc.authorwosidcekmen, mustafa baki/G-6122-2011
dc.contributor.authorEr, H
dc.contributor.authorGündüz, A
dc.contributor.authorÇigli, A
dc.contributor.authorTurkoz, Y
dc.contributor.authorCekmen, M
dc.date.accessioned2024-08-04T20:13:30Z
dc.date.available2024-08-04T20:13:30Z
dc.date.issued2000
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: The purpose of this study was to evaluate the presence of nitric oxide (NO) and cytokines such as interleukin 1 beta, interleukin 2 receptor (IL-2R), interleukin 6 and tumor necrosis factor a on aqueous humor after neodymium:YAG (Nd:YAG) laser posterior capsulotomy, Methods: Fifteen rabbits (30 eyes) with dense posterior capsule opacities underwent Nd:YAG capsulotomy 4 months after phacoemulsification cataract surgery. After general and topical anesthesia, Nd:YAG capsulotomy was performed using an equal number of shots and power setting on all eyes. Aqueous humor specimens were collected from each eye preoperatively and at 12, 24 and 48 h after the surgery to determine NO and cytokine levels. Results: The levels of NO and cytokines except IL-2R were significantly high as compared to preoperative levels in all eyes at 12 and 24 h postoperatively (p<0.05). Although the levels of NO and cytokines were higher than preoperative levels at 48 h, the differences were not statistically significant (p > 0.05), Conclusion: These findings suggest that NO and cytokines appear to be potential inflammatory mediators in the occurrence of early inflammation following Nd:YAG posterior capsulotomy. Copyright (C) 2000 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000055598
dc.identifier.endpage109en_US
dc.identifier.issn0030-3747
dc.identifier.issn1423-0259
dc.identifier.issue2-3en_US
dc.identifier.pmid10754443en_US
dc.identifier.scopus2-s2.0-0343091296en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage106en_US
dc.identifier.urihttps://doi.org/10.1159/000055598
dc.identifier.urihttps://hdl.handle.net/11616/93669
dc.identifier.volume32en_US
dc.identifier.wosWOS:000086669400011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofOphthalmic Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectaqueous humoren_US
dc.subjectneodymium : YAG capsulotomyen_US
dc.subjectcytokinesen_US
dc.subjectnitric oxideen_US
dc.subjectocular inflammationen_US
dc.titleQuantification of nitric oxide and cytokines in rabbit aqueous humor after neodymium:YAG laser capsulotomyen_US
dc.typeArticleen_US

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