Relation of susceptibility-weighted imaging findings with histological grade in intracranial meningiomas
| dc.contributor.author | Er, Ali | |
| dc.contributor.author | Bozdag, Mustafa | |
| dc.date.accessioned | 2022-03-16T16:04:06Z | |
| dc.date.available | 2022-03-16T16:04:06Z | |
| dc.date.issued | 2021 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Aim: We aimed to investigate the relation of susceptibility-weighted imaging (SWI) findings with histological grade in intracranial meningiomas. Materials and Methods: Histopathologically confirmed 58 intracranial meningioma patients (48 typical (low-grade meningioma), 10 atypical (high-grade meningioma)) who had undergone preoperative SWI between 2015 and 2020 were retrospectively evaluated. Tumor size, location, presence of peritumoral edema, WHO grade, low-grade meningioma subtypes and Ki-67 proliferation indexes were noted. SWI findings of intracranial meningiomas were categorized as either positive or negative based on presence/absence of intratumoral susceptibility signals (ITSSs). The origin of ITSSs in SWI-positive meningiomas was assessed with phase images and classified as calcification (SWI-C), vascular structure (SWI-V) or hemorrhage (SWI-H). Mann-Whitney U, chi-square, Fisher’s exact tests and multiple logistic regression analyses were performed for statistical assessment. Results: There was a significant association between SWI-positivity and low-grade in meningiomas (p = 0.010). A higher incidence of calcification was found in low-grade meningiomas (%60 in low-grade vs %10 in high-grade). Peritumoral edema was found to be associated with high grade in meningiomas (p = 0.032). Ki-67 proliferation index was significantly higher in high-grade meningiomas compared to low-grade. (p = 0.000). Conclusion: SWI combined with peritumoral edema may help to predict high grade in intracranial meningiomas. | en_US |
| dc.identifier.citation | Bozdag, M., & Er, A. (2021). Relation of susceptibility-weighted imaging findings with histological grade in intracranial meningiomas . Annals of Medical Research | en_US |
| dc.identifier.uri | https://hdl.handle.net/11616/56202 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Annals of Medical Research | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | Relation of susceptibility-weighted imaging findings with histological grade in intracranial meningiomas | en_US |
| dc.type | Article | en_US |
