The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible

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dc.contributor.authorEge, Bilal
dc.contributor.authorAksungur, Zeynep
dc.contributor.authorErdemli, Mehmet Erman
dc.contributor.authorAkgül, Hasan
dc.contributor.authorBağ, Harika Gözde Gözükara
dc.contributor.authorSelamoğlu, Zeliha
dc.date.accessioned2024-08-04T19:54:36Z
dc.date.available2024-08-04T19:54:36Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: The present study investigated the changes in the liver tissues of rats with experimentally fractured mandible following the use of Grape Extract (GSE) and Low Level Laser Therapy (LLLT) in healing the fracture in dentistry. Materials and Methods: 60 adult male Wistar Albino rats were randomly assigned to 5 main groups (Control, Fractured Mandible (FM), FM + GSE, FM + LLLT, FM + LLLT + GSE), and then these groups were divided into two groups of 7 and 21 days (n = 6). A vertical fracture line passing through the molar teeth was formed in the right mandibles of all subjects except for these in the control group, and the fracture was internally fixed with a four-hole microplate and four micro-screws. Malondialdehyde (MDA), reduced glutathione (GSH), superoxide dismutase (SOD), catalase (CAT) activities were analyzed to determine the changes caused by GSE and LLLT administration in rat liver tissues in fractured mandibles. Results: It was determined that MDA and SOD levels in FM group and GSH and CAT activity levels in FM + GSE group and MDA levels in FM + LLLT group and GSH and CAT levels in FM + GSE + LLLT group increased statistically significantly to the control group on days 7 and 21. Conclusion: Biochemical parameters were investigated on the 7th and the 21st days, and it was determined that the oxidative damage caused by mandibular defects could be eliminated substantially in the rat liver especially with the administration of grapeseed that has antioxidant capacity.en_US
dc.identifier.endpage133en_US
dc.identifier.issn1300-1744
dc.identifier.issue2en_US
dc.identifier.startpage127en_US
dc.identifier.trdizinid284949en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/284949
dc.identifier.urihttps://hdl.handle.net/11616/89970
dc.identifier.volume24en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTurgut Özal Tıp Merkezi Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandibleen_US
dc.typeArticleen_US

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