Determination of risk factors in obese and non-obese patients with coronary artery disease
Küçük Resim Yok
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Acta Cardiologica
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective - Obesity is a complex multifactorial chronic disorder recently classified by the American Heart Association (AHA) as a modifiable risk factor for coronary artery disease (CAD). This study was designed to assess conventional and novel risk factors in obese and non-obese patients with CAD. Methods and results - This study evaluates the association between conventional and novel coronary risk factors and CAD in obese and non-obese patients by using multivariate stepwise logistic regression analysis. The obese CAD group was identified by the following predictors of CAD: age, sex, hypertension, diabetes mellitus, smoking, family history of CAD, low level of HDL cholesterol, high LDL cholesterol, high C-reactive protein, high homocysteine. In a non-obese CAD group, the identified predictors of CAD were age, sex, hypertension, smoking, family history of CAD, levels of high C-reactive protein, and high homocysteine. Hypertension was found to be the strongest predictor for both obese (OR: 39.91, 95% confidence intervals (Cl): 5.51-280.3, p < 0.001) and non-obese (OR: 14.39, 95% CI: 4.4-25.8, p < 0.001) patients with CAD. Conclusions - From our data, we conclude that hypertension appears to be the strongest independent predictor of CAD regardless of body mass index (BMI).
Açıklama
Anahtar Kelimeler
coronary artery disease, risk factors, obese, non-obese, logistic regression
Kaynak
Acta Cardiologica
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
60
Sayı
6
