Leptin levels increase during flutamide therapy in women with polycystic ovary syndrome

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dc.authoridSahin, Ibrahim/0000-0002-6231-0034
dc.authoridTaskapan, Mehmet Cagatay/0000-0002-5273-4909;
dc.authorwosidSahin, Ibrahim/ABI-6050-2020
dc.authorwosidSerter, Rüştü/W-8968-2018
dc.authorwosidTaskapan, Mehmet Cagatay/ABI-7747-2020
dc.authorwosidŞahin, İbrahim/HHY-8303-2022
dc.authorwosidKarakurt, Feridun/KHY-4589-2024
dc.contributor.authorSahin, I
dc.contributor.authorSerter, R
dc.contributor.authorKarakurt, F
dc.contributor.authorDemirbas, B
dc.contributor.authorGuler, S
dc.contributor.authorCulha, C
dc.contributor.authorTaskapan, C
dc.date.accessioned2024-08-04T20:13:32Z
dc.date.available2024-08-04T20:13:32Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: To evaluate the serum leptin levels and the effects of flutamide treatment on the leptin levels in women with polycystic ovary syndrome (PCOS). Methods: 20 women with PCOS and 20 controls were enrolled in the study. Leptin levels and leptin response to an oral glucose tolerance test were assessed in both groups before and after a 4-week flutamide therapy period. Results: The leptin levels were similar in both groups at baseline. In the PCOS group, leptin levels and area under curve for leptin levels increased significantly after flutamide treatment. Conclusions: Women with PCOS had similar leptin levels to those of controls with similar age and body mass index. Flutamide treatment led to increased leptin levels and leptin responses to oral glucose tolerance tests in PCOS patients. Further studies are needed to gain insights into the clinical consequences of these effects of flutamide. Copyright (C) 2003 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000074037
dc.identifier.endpage236en_US
dc.identifier.issn0301-0163
dc.identifier.issue5-6en_US
dc.identifier.pmid14614228en_US
dc.identifier.scopus2-s2.0-0344826568en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage232en_US
dc.identifier.urihttps://doi.org/10.1159/000074037
dc.identifier.urihttps://hdl.handle.net/11616/93684
dc.identifier.volume60en_US
dc.identifier.wosWOS:000186526600005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofHormone Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectflutamideen_US
dc.subjectleptinen_US
dc.subjectpolycystic ovary syndromeen_US
dc.titleLeptin levels increase during flutamide therapy in women with polycystic ovary syndromeen_US
dc.typeArticleen_US

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