Testosterone and 17-OH progesteron levels in women with depression and the effects of antidepressant treatment

Basit Öğe Kaydı
dc.authoridkartalcı, şükrü/0000-0003-2560-0355
dc.authoridOzsoy, Saliha/0000-0003-2757-9641
dc.authoridUnal, Suheyla/0000-0003-3266-6256
dc.authoridUnal, Suheyla/0000-0003-3266-6256;
dc.authorwosidkartalcı, şükrü/ABI-1106-2020
dc.authorwosidOzsoy, Saliha/AAI-4726-2021
dc.authorwosidUnal, Suheyla/HJH-7559-2023
dc.authorwosidUnal, Suheyla/JVO-8367-2024
dc.authorwosidUnal, Suheyla/AAS-2388-2020
dc.contributor.authorKartalci, Sukru
dc.contributor.authorOzsoy, Saliha
dc.contributor.authorUnal, Suheyla
dc.contributor.authorEsel, Ertugrul
dc.date.accessioned2024-08-04T20:32:36Z
dc.date.available2024-08-04T20:32:36Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Women suffer from depression more often than males, indicating that sex hormones might be involved in the etiology of this disease. The aim of this study was to investigate whether testosterone and 17-OH progesterone are related to the pathophysiology of depression in depressed women. We also investigated if any alteration takes place in these hormonal variables with antidepressant treatment. Methods: Forty female inpatients suffering from a depressive episode and 20 healthy female controls were recruited in the study. In the patient and control groups, serum total testosterone, 17-OH progesterone and SHBG levels were assayed. Pharmacotherapy was given to the patient group for 6-10 weeks (venlafaxine n=19, fluoxetine n=12, imipramine n=9). Hormonal measurements were repeated after the treatment in the patient group who responded to antidepressant treatment. Results: Serum testosterone levels were higher in the depressive women than in the healthy women. The testosterone levels were normalized by antidepressant treatment. 17-OH progesterone and SHBG levels did not differ between patients and controls. Conclusions: The result of normalized testosterone levels with pharmacotherapy suggests that testosterone may have a relationship with depression. Elevated levels of testosterone in depressed women might be a result of over activation of the adrenal glands, which are the main source of this hormone in women. (Anatolian Journal of Psychiatry 2010; 11:285-292)en_US
dc.identifier.endpage292en_US
dc.identifier.issn1302-6631
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-78649267803en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage285en_US
dc.identifier.urihttps://hdl.handle.net/11616/95185
dc.identifier.volume11en_US
dc.identifier.wosWOS:000282764100001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherCumhuriyet Univ Tip Fak Psikiyatri Anabilim Dalien_US
dc.relation.ispartofAnadolu Psikiyatri Dergisi-Anatolian Journal of Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecttestosteroneen_US
dc.subjectprogesteroneen_US
dc.subjectdepressionen_US
dc.subjectwomanen_US
dc.titleTestosterone and 17-OH progesteron levels in women with depression and the effects of antidepressant treatmenten_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu