Investigation of propolis’ effect on thiobarbituric acid reactive substances and anti-oxidant enzyme levels of hippocampus in diabetic rats induced by streptozotocin

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dc.authorscopusid57053813100
dc.authorscopusid10639851500
dc.authorscopusid11738762300
dc.contributor.authorKöksal B.
dc.contributor.authorHanifi Emre M.
dc.contributor.authorPolat A.
dc.date.accessioned2024-08-04T20:02:36Z
dc.date.available2024-08-04T20:02:36Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBACKGROUND: Propolis is an organic resinous viscous substance collected from flower bud and plant sprig by bees. Propolis has a potential treatment agent for oxidative damage caused by diabetes in hippocampus due to its flavonoid and phenolic content. AIM: In this study effect of propolis on thiobarbituric acid reactive substances and anti-oxidative enzyme levels of hippocampus in diabetic rats induced by streptozotocin was investigated. MATERIALS AND METHODS: The study involved measuring levels of SOD, CAT, GSH-Px and TBARs in hippocampus tissue of STZ-induced diabetic rats (Adult Male Sprague Dawley rats) after applying propolis for one month. The subjects of the study were composed of 51 rats randomly assigned to four groups (Control, STZ, P+STZ and STZ+P). For analysis of data, Kruskal Wallis Test was utilized. RESULTS: The findings of the study showed that there were no significant difference in the levels of TBARS, SOD, CAT and GSH-Px of hippocampus across the groups. CONCLUSION: Propolis application in four-week duration does not have effect on TBARS, SOD, CAT and GSH-Px levels of hippocampus of diabetic rats. These findings mean that more time for observing oxidative harms on hippocampus is needed. © 2015 Burcu Köksal, Memet Hanifi Emre, Alaadin Polat.en_US
dc.identifier.doi10.3889/oamjms.2015.031
dc.identifier.endpage56en_US
dc.identifier.issn1857-9655
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84930481805en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage52en_US
dc.identifier.urihttps://doi.org/10.3889/oamjms.2015.031
dc.identifier.urihttps://hdl.handle.net/11616/91820
dc.identifier.volume3en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofOpen Access Macedonian Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnti-oxidative enzymesen_US
dc.subjectDiabetesen_US
dc.subjectPropolisen_US
dc.subjectRatsen_US
dc.subjectStreptozotocineen_US
dc.titleInvestigation of propolis’ effect on thiobarbituric acid reactive substances and anti-oxidant enzyme levels of hippocampus in diabetic rats induced by streptozotocinen_US
dc.typeArticleen_US

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