An Investgation About the Relationship Between Vasopressin and Oxytocin in Persistent Type Functional Neurological Symptom Disorder

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dc.authoridYeşil Örnek, Bahar/0000-0003-0873-4589
dc.authorwosidYeşil Örnek, Bahar/AAB-4751-2022
dc.contributor.authorOrnek, Bahar Yesil
dc.contributor.authorCumurcu, Birgul Elbozan
dc.contributor.authorZayman, Esra Porgali
dc.date.accessioned2024-08-04T20:50:46Z
dc.date.available2024-08-04T20:50:46Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective Functional neurogical symptom disorder (FNSD) is a somatic symptom disorder with loss of voluntary motor or sensory functions, which cannot be explained by another medical condition. The study aimed to examine the relationship of vasopressin and oxytocin in persistent type FNSD. Methods This study included 27 female patients between the ages of 20-57 who were diagnosed with FNSD according to DSM-5 and 27 healthy controls matched in terms of age and gender. Serum vasopressin and oxytocin levels were measured twice on the same day in fasting blood samples and the results were compared statistically. Results Vasopressin were lower in patients compared to controls while there was no difference between oxytocin levels. Childhood traumas were more common in patient group, and mean oxytocin level was lower in patients who exposed to childhood trauma, compared to controls. No significant difference was found between the groups in terms of vasopressin. Conclusion Changes in vasopressin and oxytocin balance in the pathogenesis of persistant FNSD, may likely to lead to physiological and behavioral consequences. Lower oxytocin levels may also be a marker of exposure to childhood trauma in FNSD. These neuropeptides plays important role in neuroendocrine balance of emotional behavior. Psychiatry Investig 2021;18(10):1018-1024en_US
dc.description.sponsorshipScientific Research Fund of Inonu University (IUBAP) [2013/81]en_US
dc.description.sponsorshipThis study was supported by Scientific Research Fund of Inonu University (IUBAP) under Grant 2013/81 number.en_US
dc.identifier.doi10.30773/pi.2021.0040
dc.identifier.endpage1024en_US
dc.identifier.issn1738-3684
dc.identifier.issn1976-3026
dc.identifier.issue10en_US
dc.identifier.pmid34666429en_US
dc.identifier.scopus2-s2.0-85117592905en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1018en_US
dc.identifier.urihttps://doi.org/10.30773/pi.2021.0040
dc.identifier.urihttps://hdl.handle.net/11616/100276
dc.identifier.volume18en_US
dc.identifier.wosWOS:000714051800012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Neuropsychiatric Assocen_US
dc.relation.ispartofPsychiatry Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOxytocinen_US
dc.subjectVasopressinen_US
dc.subjectFunctional neurological symptom disorderen_US
dc.subjectChildhood traumaen_US
dc.titleAn Investgation About the Relationship Between Vasopressin and Oxytocin in Persistent Type Functional Neurological Symptom Disorderen_US
dc.typeArticleen_US

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