Investigation of propolis effects on learning and memory of diabetic Sprague dawley rats induced by streptozotocin
Küçük Resim Yok
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Scibulcom Ltd.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The purpose of this study is to investigate possible effects of propolis on learning and memory functions of diabetic rats induced by streptozotocin (STZ). In the study, 51 young male adult Sprague Dawley rats were involved and the rats were exposed to eight-arm radial maze applications for evaluation of their learning and memory functions during 4 weeks. In the first three weeks latent learning was observed while short and long term memory functions were observed in the last week. The rats were assigned into four different groups: control (n = 14), only STZ application (n = 12), propolis application before STZ exposure (n = 12) and propolis application after STZ exposure (n = 13). The findings showed that no significant effect of propolis on latent learning, short and long term memory functions of diabetic rats was determined; moreover diabetes did not lead to harms on latent learning, short and long term memory functions. In conclusion, it can be said that the time might not be enough to detect learning and memory dysfunctions caused by diabetes and effects of propolis, however it is seen that propolis is an effective chemical in decreasing blood glucose levels of diabetic rats.
Açıklama
Anahtar Kelimeler
Diabetes mellitus, Eight-arm radial maze, Learning, Memory, Propolis, Streptozotocin
Kaynak
Oxidation Communications
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
40
Sayı
1-II
