Choroidal thickness in relation to sex, age, refractive error, and axial length in healthy Turkish subjects

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dc.authoridtuncer, ibrahim/0000-0002-0038-971X
dc.authoridPolat, Nihat/0000-0002-1735-1363
dc.authoridAtalay, Eray/0000-0002-2536-4279;
dc.authorwosidtuncer, ibrahim/AAA-1987-2021
dc.authorwosidPolat, Nihat/ABI-7316-2020
dc.authorwosidAtalay, Eray/O-5377-2018
dc.authorwosidZengin, MO/B-2222-2014
dc.authorwosidkarahan, eyyup/U-2977-2017
dc.contributor.authorTuncer, Ibrahim
dc.contributor.authorKarahan, Eyyup
dc.contributor.authorZengin, Mehmet Ozgur
dc.contributor.authorAtalay, Eray
dc.contributor.authorPolat, Nihat
dc.date.accessioned2024-08-04T20:40:17Z
dc.date.available2024-08-04T20:40:17Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to investigate the association between choroidal thickness (CT) and sex, age, refractive error (RE), and axial length in healthy subjects. This is a study of 154 eyes in 154 healthy subjects. CT measurements were performed by the same experienced technician using a spectral domain optical coherence tomography device. CT was measured perpendicularly from the outer edge of the retinal pigment epithelium to the choroid-sclera boundary at the fovea and at six more points which are located at, respectively, 500 A mu m nasal to the fovea, 1,000 A mu m nasal to the fovea, and 1,500 mu m nasal to the fovea, 500 mu m temporal to the fovea, 1,000 mu m temporal to the fovea, and 1,500 mu m temporal to the fovea. The RE was measured by autorefractometry, and the axial length was measured by interferometry. Statistical analysis was performed to evaluate CT at each location, and to the correlations of CT with sex, age, RE, and axial length. The mean subfoveal CT was 265.86 +/- A 60.32 A mu m, the mean age was 49.01 +/- A 19.19 years, the mean RE was -0.17 +/- A 1.20 diopters (D), and the mean axial length was 23.39 +/- A 0.76 mm. CT profile indicated that the choroid was thicker at the fovea than at temporal and nasal locations. Univariable linear regression analysis showed that subfoveal CT decreased 3.14 A mu m for each year of age and decreased 79.33 A mu m for each mm of axial length (P = 0.000, R (2) = 0.249; P = 0.000, R (2) = 0.487, respectively). In a similar analysis, subfoveal CT was found to decrease by 50.24 A mu m/D myopia-shifted change in refraction (P = 0.000, R (2) = 0.201). The subfoveal choroid was 99.16 A mu m (39.22 %) thicker in men than women when adjusting for age and axial length (P = 0.000, R (2) = 0.249). CT decreases with increasing myopia, age, and axial length. Men had thicker choroid than women, and CT varies depending on location.en_US
dc.identifier.doi10.1007/s10792-014-9962-4
dc.identifier.endpage410en_US
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue3en_US
dc.identifier.pmid24950905en_US
dc.identifier.scopus2-s2.0-84930938216en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage403en_US
dc.identifier.urihttps://doi.org/10.1007/s10792-014-9962-4
dc.identifier.urihttps://hdl.handle.net/11616/96819
dc.identifier.volume35en_US
dc.identifier.wosWOS:000353827300014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOptical Coherence Tomographyen_US
dc.subjectMyopic Eyesen_US
dc.titleChoroidal thickness in relation to sex, age, refractive error, and axial length in healthy Turkish subjectsen_US
dc.typeArticleen_US

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