Postoperative pulmonary complications after liver transplantation assessment of risk factors for mortality

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dc.authorid131825en_US
dc.authorid101741en_US
dc.authorid134023en_US
dc.authorid109262en_US
dc.authorid9712en_US
dc.authorid112689en_US
dc.contributor.authorAydın, Cemalettin
dc.contributor.authorOtan, Emrah
dc.contributor.authorAkbulut, Ahmet Sami
dc.contributor.authorOtan, Emrah
dc.contributor.authorAkbulut, Ahmet Sami
dc.contributor.authorKarakaş, Serdar
dc.contributor.authorKayaalp, Cüneyt
dc.contributor.authorKaragül, Servet
dc.contributor.authorÇolak, Cemil
dc.contributor.authorYılmaz, Sezai
dc.date.accessioned2017-12-21T06:24:21Z
dc.date.available2017-12-21T06:24:21Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.descriptionTransplantation Proceedings, 5(1), 1488–1494.en_US
dc.description.abstractBackground. The aim of this study was to identify the risk factors related to mortality in liver transplant (LT) patients with post-transplantation pulmonary complications. Method. Patients who underwent liver transplantation in our clinic between January 2010 and January 2012 were retrospectively reviewed for post-transplantation pulmonary complications. Demographic, clinical, radiologic, and postoperative chart data of 153 patients with pulmonary complications were analyzed using an independent samples Student t test, Pearson’s c2 test, Fisher’s exact test, and Yate’s corrected c2 test. Mortality was analyzed using a multiple logistic regression model. The best-fit breakpoint resulting in a cut-off value for the variables of interest was determined using ROC curves and the Youden index. Results. The 153 patients with pulmonary complication were divided into 2 groups: mortality (n ¼ 53) and survival (n ¼ 100). Univariate analyses showed significant differences between these 2 groups with respect to MELD score (P ¼ .035), duration of mechanical ventilation (P > .001), pneumonia (P ¼ .01), and endotracheal culture results (P ¼ .001). In the multivariate analysis, hemoglobin (P ¼ .03, odds ratio [OR]: 1.239), MELD score (P ¼ .027, OR: 1.064), duration of mechanical ventilation (P ¼ .003, OR: 1.091), and age (P ¼ .042, OR: 1.001) were significant risk factors for mortality. The best-fit breakpoint analysis yielded cut-off values for hemoglobin (>11.2, sensitivity: 50.9%, specificity: 70%), MELD score (>16, sensitivity: 73.6%, specificity: 42%) and duration of mechanical ventilation (>3, sensitivity: 62.3%, specificity: 76%). Conclusion. Advanced age, high hemoglobin level, high MELD score, and long-term mechanical ventilation are significant risk factors for mortality in liver transplant patients with postoperative pulmonary complications.en_US
dc.identifier.citationAydın, C., Otan, E., Akbulut, A. S., Karakaş, S., Kayaalp, C., Karagül, S., … Yılmaz, S. (2015). Postoperative Pulmonary Complications After Liver Transplantation Assessment Of Risk Factors For Mortality. Transplantation Proceedings, 5(1), 1488–1494.en_US
dc.identifier.endpage1494en_US
dc.identifier.issue1en_US
dc.identifier.startpage1488en_US
dc.identifier.urihttps://ac.els-cdn.com/S0041134515003838/1-s2.0-S0041134515003838-main.pdf?_tid=849a2314-e616-11e7-be22-00000aab0f6b&acdnat=1513837185_21eadc9c7f6f8baaae0584b662afc829
dc.identifier.urihttps://hdl.handle.net/11616/7915
dc.identifier.volume5en_US
dc.language.isoenen_US
dc.publisherTransplantation Proceedingsen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titlePostoperative pulmonary complications after liver transplantation assessment of risk factors for mortalityen_US
dc.typeArticleen_US

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