Is airborne transmission of Acinetobacter baumannii possible: A prospective molecular epidemiologic study in a tertiary care hospital

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dc.authoridBayindir, Yasar/0000-0003-3930-774X
dc.authoridOTLU, BARIS/0000-0002-6220-0521
dc.authoridErsoy, Yasemin/0000-0001-5730-6682
dc.authoridKayabas, Uner/0000-0002-5323-0796
dc.authorwosidBayindir, Yasar/T-1523-2017
dc.authorwosidOTLU, BARIS/ABI-5532-2020
dc.authorwosidYAKUPOGULLARI, YUSUF/F-3966-2011
dc.authorwosidErsoy, Yasemin/AAE-4811-2020
dc.authorwosidKayabas, Uner/JRX-1616-2023
dc.contributor.authorYakupogullari, Yusuf
dc.contributor.authorOtlu, Baris
dc.contributor.authorErsoy, Yasemin
dc.contributor.authorKuzucu, Cigdem
dc.contributor.authorBayindir, Yasar
dc.contributor.authorKayabas, Uner
dc.contributor.authorTogal, Turkan
dc.date.accessioned2024-08-04T20:42:50Z
dc.date.available2024-08-04T20:42:50Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Understanding the dynamics of aerial spread of Acinetobacter may provide useful information for production of effective control measurements. We investigated genetic relationships between air and clinical isolates of Acinetobacter baumannii in an intensive care unit (ICU) setting. Methods: We conducted a prospective surveillance study in a tertiary care hospital for 8 months. A total of 186 air samples were taken from 2 ICUs. Clonal characteristics of air isolates were compared with the prospective clinical strains and the previously isolated strains of ICU patients over a 23-month period. Results: Twenty-six (11.4%) air samples yielded A baumannii, of which 24 (92.3%) isolateswere carbapenemresistant. The Acinetobacter concentrationwas the highest in bedside sampling areas of infected patients (0.39 CFU/m(3)). Air isolateswere clustered in 13 genotypes, and 7 genotypes (including 18 air strains) were clonally related to the clinical strains of 9 ICU patients. One clone continued to be cultured over 27 days in ICU air, and air isolates could be clonally related to 7-week retrospective and approximately 15-week prospective clinical strains. Conclusions: The results of this study suggest that infected patients could spread significant amounts of Acinetobacter to ICU air. These strains could survive in air for some weeks and could likely still infect new patients after some months. Special control measurements may be required against the airborne spread of Acinetobacter in ICUs. (C) 2016 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajic.2016.05.022
dc.identifier.endpage1599en_US
dc.identifier.issn0196-6553
dc.identifier.issn1527-3296
dc.identifier.issue12en_US
dc.identifier.pmid27561435en_US
dc.identifier.scopus2-s2.0-84998879849en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1595en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajic.2016.05.022
dc.identifier.urihttps://hdl.handle.net/11616/97602
dc.identifier.volume44en_US
dc.identifier.wosWOS:000392626300032en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMosby-Elsevieren_US
dc.relation.ispartofAmerican Journal of Infection Controlen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIntensive care uniten_US
dc.subjectHealth care-associated infectionen_US
dc.subjectAerial spreaden_US
dc.subjectEnvironmental samplingen_US
dc.titleIs airborne transmission of Acinetobacter baumannii possible: A prospective molecular epidemiologic study in a tertiary care hospitalen_US
dc.typeArticleen_US

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