Severe preeclampsia and fetal virilization in a spontaneous singleton pregnancy complicated by hyperreactio luteinalis

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dc.authorwosidSimsek, Yavuz/AAH-9894-2021
dc.contributor.authorSimsek, Y.
dc.contributor.authorCelen, S.
dc.contributor.authorUstun, Y.
dc.contributor.authorDanisman, N.
dc.contributor.authorBayramoglu, H.
dc.date.accessioned2024-08-04T20:35:51Z
dc.date.available2024-08-04T20:35:51Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Hyperreactio luteinalis is a rare condition that stems from theca cell hyperplasia in the ovaries due to a high level of human chorionic gonadotropin during gestation. It occurs commonly in pregnant patients with trophoblastic disease, occasionally in multiple pregnancies, and rarely in normal singleton pregnancy. Case Report: A 24-year-old pregnant woman, G3 P0, who was admitted to the Perinatology Clinic with increasing findings of virilization during pregnancy was presented. The patient had bilaterally enlarged multicystic ovaries on sonographic examination and elevated serum androgen levels She was managed conservatively until 38th week of gestation as a presumptive diagnosis of hyperreactio luteinalis. Elevated blood pressure and prominent proteinuria were detected during the follow-up of the patient and labor was induced. She underwent an emergency caesarean delivery because of fetal distress. During caesarean section, ovarian biopsies were taken and a histopathological diagnosis of hyperreactio luteinalis was determined. The female fetus also presented virilization. Conclusion: Although infrequent, hyperreactio luteinalis with both maternal and fetal virilization can occur in women with spontaneous singleton pregnancies. The clinical manifestations in such women may be complicated by severe preeclampsia.en_US
dc.identifier.endpage121en_US
dc.identifier.issn1128-3602
dc.identifier.issue1en_US
dc.identifier.pmid22338557en_US
dc.identifier.scopus2-s2.0-84859851431en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage118en_US
dc.identifier.urihttps://hdl.handle.net/11616/95626
dc.identifier.volume16en_US
dc.identifier.wosWOS:000300114800016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHyperreactio luteinalisen_US
dc.subjectHyperandrogenemiaen_US
dc.subjectPregnancyen_US
dc.subjectPreeclampsiaen_US
dc.titleSevere preeclampsia and fetal virilization in a spontaneous singleton pregnancy complicated by hyperreactio luteinalisen_US
dc.typeArticleen_US

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