The Effect of Dexamethasone in Tramadol Induced Nausea and Vomiting
| dc.contributor.author | Gülhaş, Nurçin | |
| dc.contributor.author | Şanlı, Mukadder | |
| dc.contributor.author | Aslan, Abdul Vahap | |
| dc.contributor.author | Özgül, Ülkü | |
| dc.contributor.author | Bicakcioğlu, Murat | |
| dc.contributor.author | Durmuş, Mahmut | |
| dc.date.accessioned | 2021-11-26T12:42:08Z | |
| dc.date.available | 2021-11-26T12:42:08Z | |
| dc.date.issued | 2016 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Abstract: We aimed to investigate the efficacy of a single dose bolus of dexamethasone on tramadol induced nausea and vomiting in our study. After approval was taken from ethics committee and patients, a total of 60 ASA I-II patients who were planned to undergo total abdominal hysterectomy (TAH) under general anesthesia were included in this study. A patient-controlled analgesia device was explained for the patients with preoperative visit. After the non-premedicated patients were taken in the operation room, the routine monitorization was performed. Induction was provided with 1?g/kg of fentanyl, 2 mg/kg propofol and 0.1 mg/kg vecuronium. 6-8% concentration of desflurane in a mixture of 50% air and 50% O2 was used for maintenance of anesthesia. When the incision was started to be closed, the patients were randomized into two groups by envelope method. 8 mg iv dexamethasone (2 mL) was given for Group D (n=30), iv Saline solution (2 mL) was given for Group K (n=30). After the incision was closed, a loading dose of intravenous tramadol 1 mg/kg was administered in both groups. The patients were taken in the postanesthesia care unit by extubating following the antagonism of muscle relaxant at the end of surgery. The patient-controlled analgesia device was scheduled to be as infusion: no, bolus: 12 mg, lock-out time: 10 min, 24 hour dosing limit: 400 mg. The pain and nausea and vomiting scores, additional analgesic and antiemetic requirements, the total amount of tramadol consumption were recorded at post-operative recovery and postoperative 2, 4, 6, 12 and 24 hours. Although the incidence of nausea and vomiting, and pain scores at 2 and 4 hours were not statistically significant, they were lower in Gorup D compared to Group K (p>0.05). 14 patients in Group K required additional antiemetics and 12 patients in Group D required additional antiemetics (p>0.05). Six patients in Group K required additional analgesics and 4 patients in Group D required additional analgesics. Although the total amount of tramadol consumption was not statistically significant, it was lower in Group D compared to Group K. It was concluded that a single bolus dose of dexamethasone 8 mg has not reduced tramadol induced nausea and vomiting in patients who were planned to undergo TAH | en_US |
| dc.identifier.citation | GÜLHAŞ N,ŞANLI M,ASLAN A. V,ÖZGÜL Ü,BİCAKCİOGLU M,DURMUŞ M (2016). The Effect of Dexamethasone in Tramadol Induced Nausea and Vomiting. Medicine Science, 5(1), 94 - 101. | en_US |
| dc.identifier.endpage | 101 | en_US |
| dc.identifier.issn | 2147-0634 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.startpage | 94 | en_US |
| dc.identifier.trdizinid | 260982 | en_US |
| dc.identifier.uri | https://hdl.handle.net/11616/43481 | |
| dc.identifier.uri | https://search.trdizin.gov.tr/yayin/detay/260982 | |
| dc.identifier.volume | 5 | en_US |
| dc.indekslendigikaynak | TR-Dizin | en_US |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Medicine Science | en_US |
| dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | The Effect of Dexamethasone in Tramadol Induced Nausea and Vomiting | en_US |
| dc.type | Article | en_US |
