Hepatic Artery Thrombosis-Related Risk Factors After Living Donor Liver Transplantation: Single-Center Experience From Turkey

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dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidKayaalp, Cuneyt/AAH-1764-2021
dc.contributor.authorUnal, B.
dc.contributor.authorGonultas, F.
dc.contributor.authorAydin, C.
dc.contributor.authorOtan, E.
dc.contributor.authorKayaalp, C.
dc.contributor.authorYilmaz, S.
dc.date.accessioned2024-08-04T20:37:33Z
dc.date.available2024-08-04T20:37:33Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description9th Congress of the Turkish-Transplantation-Centers-Coordination-Association (TTCCA) -- SEP 26-29, 2012 -- Bursa, TURKEYen_US
dc.description.abstractAim. The purpose of this retrospective study is to evaluate the risk factors hepatic artery thrombosis (HAT) after orthotopic liver transplantation (OLT) in a consecutive series from a single center. Materials and Methods. Between January 2010 and May 2012, we performed 278 living donor liver transplantations, including 189 males and 89 females. We compared the risk factors between HAT and non-HAT groups according to the following variables: age, gender, body mass index (BMI), graft weight, use of graft, Child-Pugh and model for end stage liver disease score, level of hemoglobin, blood pressure, operation time, blood transfusion, presence of ascites, international normalized ratio (INR) level, and etiology. Results. Eighteen patients, including 15 males and 3 female, had HAT after the operation (mean age, 45.1 years; age range, 22-60 years). There were no pediatric patients in the HAT group. HAT rate was 6.5% in our series. Graft loss and retransplantation due to HAT was 38.7% in a 2-year period. Biliary leakage was observed in 72 (25.8%) living donor liver transplantations; this rate was higher in patients with HAT (n = 8; 44.4%). The infection rate was 50% (n = 9) in the HAT group and was 32.7% (n = 91) in the non-HAT group. Mean INR value was 2.15 in the HAT group and 1.72 in the non-HAT group. When we compared the groups according to use of graft for anastomosis, biliary lekage, infection, and INR value, the differences were statistically significant (P < .05). Conclusion. Although the results of OLT have improved over the past years, HAT is still associated with substantial morbidity, high incidence of graft failure, and high mortality rates. The most important findings associated with HAT in our series were found as INR levels, bile leakage, and resistant infections. Use of vascular graft for hepatic artery anastomosis was found to increase HAT risk.en_US
dc.description.sponsorshipTurkish Transplantat Ctr Coordinat Assoc (TTCCA)en_US
dc.identifier.doi10.1016/j.transproceed.2013.02.070
dc.identifier.endpage977en_US
dc.identifier.issn0041-1345
dc.identifier.issue3en_US
dc.identifier.pmid23622602en_US
dc.identifier.scopus2-s2.0-84876820010en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage974en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2013.02.070
dc.identifier.urihttps://hdl.handle.net/11616/96032
dc.identifier.volume45en_US
dc.identifier.wosWOS:000318457000034en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectUrgent Revascularizationen_US
dc.subjectSplenic Arteryen_US
dc.subjectVascular Complicationsen_US
dc.subjectReconstructionen_US
dc.subjectGraften_US
dc.subjectVeinen_US
dc.titleHepatic Artery Thrombosis-Related Risk Factors After Living Donor Liver Transplantation: Single-Center Experience From Turkeyen_US
dc.typeConference Objecten_US

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