Brain Perfusion MRI Findings in Patients with Behcet's Disease

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dc.authoridKamisli, Suat/0000-0003-4281-3301
dc.authorwosidKamisli, Suat/JZT-8388-2024
dc.authorwosidKamisli, Suat/JVN-4663-2024
dc.authorwosidKamisli, Suat/AAC-2706-2021
dc.contributor.authorAlkan, Alpay
dc.contributor.authorGoktan, Asli
dc.contributor.authorKarincaoglu, Yelda
dc.contributor.authorKamisli, Suat
dc.contributor.authorDogan, Metin
dc.contributor.authorOztanir, Namik
dc.contributor.authorTuran, Nergiz
dc.date.accessioned2024-08-04T20:35:53Z
dc.date.available2024-08-04T20:35:53Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective. To search brain perfusion MRI (pMRI) changes in Behcet's disease (BD) with or without neurological involvement. Materials and Method. The pMRI were performed in 34 patients with BD and 16 healthy controls. Based on neurologic examination and post-contrast MRI, 12 patients were classified as Neuro-Behcet (group 1, NBD) and 22 patients as BD without neurological involvement (group 2). Mean transit time (MTT), time to peak (TTP), relative cerebral blood volume (rCBV), and relative cerebral blood flow (rCBF) were obtained and compared to those of healthy control group (group 3). Results. There was a significant difference in the MTT and rCBF within the pons and parietal cortex in groups 1 and 2. rCBV increased in cerebral pedicle in group 1 compared with groups 2 and 3. In the temporal lobe white matter, prolonged MTT and decreased rCBF were found in groups 1 and 2. In the corpus striatum, internal capsule, and periventricular white matter, rCBF increased in group 1 compared with group 3 and decreased in groups 1 and 2. Conclusion. Brain pMRI is a very sensitive method to detect brain involvement in patients with BD and aids the clinical diagnosis of NBD, especially in patients with negative MRI findings.en_US
dc.identifier.doi10.1100/2012/261502
dc.identifier.issn1537-744X
dc.identifier.pmid22654579en_US
dc.identifier.scopus2-s2.0-84861071886en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1100/2012/261502
dc.identifier.urihttps://hdl.handle.net/11616/95651
dc.identifier.wosWOS:000304774000001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHindawi Publishing Corporationen_US
dc.relation.ispartofScientific World Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDiffusionen_US
dc.subjectInvolvementen_US
dc.subjectSpecten_US
dc.subjectVasculitisen_US
dc.titleBrain Perfusion MRI Findings in Patients with Behcet's Diseaseen_US
dc.typeArticleen_US

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