The impact of thyroid-stimulating hormone levels in euthyroid women on intrauterine insemination outcome

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dc.authoridKaraer, Abdullah/0000-0002-2010-6211
dc.authoridCOSKUN, Ebru INCI/0000-0003-4402-3725
dc.authorwosidKaraer, Abdullah/ABI-4667-2020
dc.authorwosidTuncay, Görkem/ABI-6418-2020
dc.authorwosidCOSKUN, Ebru INCI/ABI-8238-2020
dc.contributor.authorTuncay, Gorkem
dc.contributor.authorKaraer, Abdullah
dc.contributor.authorCoskun, Ebru Inci
dc.contributor.authorBaloglu, Demet
dc.contributor.authorTecellioglu, Ayse Nihan
dc.date.accessioned2024-08-04T20:44:24Z
dc.date.available2024-08-04T20:44:24Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: The aim of this study was to examine the effect of thyroid-stimulating hormone (TSH) levels on intrauterine insemination (IUI) outcomes among euthyroid women. Methods: A retrospective cohort study was conducted. A total of 302 women who started their first IUI cycle in our fertility center were included in this study. The patients were categorized into two groups based on their preconception TSH values: 0.38-2.49 mIU/L and 2.50-4.99 mIU/L. The clinical pregnancy rate was the main outcome parameter. As secondary parameters, we evaluated the differences in spontaneous abortion rate, live-birth delivery rate, and perinatal outcomes according to the preconception TSH threshold (< 2.5 and < 5.00 mIU/L). Results: There was no significant difference between the two groups with respect to clinical pregnancy, miscarriage, and live-birth rates with an odds ratio of 1.67 (95% CI: 0.79-3.53), 1.08 (95% CI: 0.09-13.1), and 1.79 (95% CI: 0.77-4.2), respectively. In addition, there were no significant differences in perinatal outcomes (gestation at delivery, birth weight, and neonatal intensive care unit-administration rate) between the two groups. Conclusions: Our findings indicate that among euthyroid patients, preconception TSH values in the high-normal range (between 2.5 and 4.9 mIU/L) do not have a negative effect on IUI outcomes.en_US
dc.identifier.doi10.1186/s12905-018-0541-0
dc.identifier.issn1472-6874
dc.identifier.pmid29558997en_US
dc.identifier.scopus2-s2.0-85044187628en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1186/s12905-018-0541-0
dc.identifier.urihttps://hdl.handle.net/11616/98204
dc.identifier.volume18en_US
dc.identifier.wosWOS:000427984100001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofBmc Womens Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInfertilityen_US
dc.subjectIntrauterine inseminationen_US
dc.subjectThyroiden_US
dc.subjectTSHen_US
dc.titleThe impact of thyroid-stimulating hormone levels in euthyroid women on intrauterine insemination outcomeen_US
dc.typeArticleen_US

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