Alterations in the dimensions of aortopulmonary septum in hypertensive subjects

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dc.authoridIrmak, M. Kemal/0000-0002-1903-8303
dc.authoridUzun, Mehmet/0000-0003-2999-489X
dc.authorwosidYazar, Fatih/JZD-3911-2024
dc.authorwosidFadillioglu, Ersin/K-3817-2019
dc.authorwosidIrmak, M. Kemal/H-6667-2014
dc.contributor.authorIrmak, MK
dc.contributor.authorErinc, K
dc.contributor.authorYazar, F
dc.contributor.authorUzun, M
dc.contributor.authorFadillioglu, E
dc.contributor.authorOzer, M
dc.date.accessioned2024-08-04T20:13:29Z
dc.date.available2024-08-04T20:13:29Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe neural crest origin of the aortopulmonary septum has led us to investigate the septum for a special function, and we designed the present study to assess the alteration, if any, in the dimensions of the aortopulmonary septum in hypertension. The dimensions of the aortopulmonary septum were measured by echocardiography in 36 hypertensive and 36 age- and sex-matched normotensive subjects. Echocardiographic examination included measurement of the cross-sectional area of the aortopulmonary septum with standard two-dimensional views from the parasternal windows. Standardization of this dimension with appropriate cardiac measurements such as aortic and internal left ventricular diameters was also performed to provide growth-independent estimates of septal size. The average area of the septum in the hypertensive group was 2.18+/-30.391 cm(2), significantly lower than that in the normotensive group (2.370+/-0.415 cm(2)). There were also significant differences in the area of the aortopulmonary septum between the groups when the values were standardized with internal left ventricular diameters. In conclusion, these data confirm that the aortopulmonary septum is smaller in hypertensive than in normotensive humans. This difference might be the result of a possible function of the aortopulmonary septum in blood pressure regulation.en_US
dc.identifier.doi10.1291/hypres.26.783
dc.identifier.endpage787en_US
dc.identifier.issn0916-9636
dc.identifier.issn1348-4214
dc.identifier.issue10en_US
dc.identifier.pmid14621180en_US
dc.identifier.scopus2-s2.0-0242525171en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage783en_US
dc.identifier.urihttps://doi.org/10.1291/hypres.26.783
dc.identifier.urihttps://hdl.handle.net/11616/93653
dc.identifier.volume26en_US
dc.identifier.wosWOS:000186252200002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherNature Publishing Groupen_US
dc.relation.ispartofHypertension Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectaortopulmonary septumen_US
dc.subjectdimensionen_US
dc.subjecthypertensionen_US
dc.titleAlterations in the dimensions of aortopulmonary septum in hypertensive subjectsen_US
dc.typeArticleen_US

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