The degree of fluid absorption during hysteroscopic surgery in patients pretreated with goserelin

Basit Öğe Kaydı
dc.authorwosidtaskin, omur/C-6864-2016
dc.contributor.authorTaskin, O
dc.contributor.authorYalcinoglu, A
dc.contributor.authorKucuk, S
dc.contributor.authorBurak, F
dc.contributor.authorOzekici, U
dc.contributor.authorWheeler, JM
dc.date.accessioned2024-08-04T20:11:50Z
dc.date.available2024-08-04T20:11:50Z
dc.date.issued1996
dc.departmentİnönü Üniversitesien_US
dc.descriptionAmerican-Association-of-Gynecologic-Laparoscopists 24th Annual Meeting -- NOV 08-12, 1995 -- ORLANDO, FLen_US
dc.description.abstractStudy Objective. To assess the effects of pretreatment with the gonadotropin-releasing hormone analog goserelin on fluid absorption in patients undergoing hysteroscopic endometrial ablation. Design. Prospective, randomized, placebo-controlled study. Setting. A university-based clinic. Patients. Thirteen women with dysfunctional uterine bleeding who were scheduled for electrosurgical hysteroscopic ablation. interventions. Seven women were randomized to receive luteal phase goserelin 3.75 mg and six saline in the menstrual cycle approximately 10 weeks before surgery. Operative hysteroscopy was carried out with glycine 1.5% mixed with 2% alcohol medium under constant pressure as an irrigant. The amount of irrigant used, irrigant deficit, blood levels of albumin and ethanol, hematocrit, hemoglobin, changes in sodium levels, and central venous pressure were compared between the groups. Measurements and Main Results. All of the patients had an unsuccessful course of medical therapy for at least 3 months and a normal endometrial biopsy. The age, weight, and uterine size were similar between the groups. The mean volume of irrigant used and operating time were similar in both groups (4.18 +/- 0.2 vs 4.5 +/- 0.5 L, and 33.7 +/- 1.5 vs 37 +/- 2.1 min). Although operating time, volume deficit, decrease in protein level, and hematocrit were less in the goserelin than in the saline group, the differences were not statistically significant (p >0.05). The ethanol levels in blood, decrease in Na+, and irrigant deficit were significantly lower in the goserelin than in the saline group (17.4 +/- 3.8 vs 25.3 +/- 4.2 mg/ml, 6.7 +/- 1.2 vs 9.1 +/- 0.9 mEq/L, and 0.49 +/- 0.08 vs 0.66 +/- 0.05 L, respectively; p <0.05). Conclusion. Based on these results we conclude that in women undergoing hysteroscopic endometrial ablation, pretreatment with goserelin may decrease the absorption of hysteroscopic medium, prevent fluid overload, and improve the outcome possibly by causing hypovascularity and decreased endometrial growth.en_US
dc.description.sponsorshipAmer Assoc Gynecol Laparoscopistsen_US
dc.identifier.doi10.1016/S1074-3804(05)80167-7
dc.identifier.endpage559en_US
dc.identifier.issn1074-3804
dc.identifier.issue4en_US
dc.identifier.pmid9050688en_US
dc.identifier.scopus2-s2.0-0029737546en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage555en_US
dc.identifier.urihttps://doi.org/10.1016/S1074-3804(05)80167-7
dc.identifier.urihttps://hdl.handle.net/11616/93023
dc.identifier.volume3en_US
dc.identifier.wosWOS:A1996WY98100012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJournal Amer Assoc Gynecologic Laparoscopistsen_US
dc.relation.ispartofJournal of The American Association of Gynecologic Laparoscopistsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEndometrial Ablationen_US
dc.subjectResectionen_US
dc.subjectHyponatremiaen_US
dc.subjectWomenen_US
dc.titleThe degree of fluid absorption during hysteroscopic surgery in patients pretreated with goserelinen_US
dc.typeConference Objecten_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu