C-reactive protein is an indicator for fatal outcomes in first-time stroke patients

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dc.authoridGÖZKE, EREN/0000-0001-6175-0647
dc.authoridKoçer, Abdulkadir/0000-0003-2866-555X
dc.authorwosidGÖZKE, EREN/A-2004-2019
dc.authorwosidKoçer, Abdulkadir/I-5287-2013
dc.contributor.authorKoçer, A
dc.contributor.authorCanbulat, C
dc.contributor.authorGözke, E
dc.contributor.authorIlhan, A
dc.date.accessioned2024-08-04T20:15:05Z
dc.date.available2024-08-04T20:15:05Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: The causal relation of high sensitivity C-reactive protein (hsCRP) to ischemic cerebrovascular disease remains unclear, though an inflammatory effect has been suggested in many studies. The aim of our study was to evaluate serum hsCRP levels in ischemic stroke patients and in a control group, and to correlate the values with other generally known risk factors. Material/Methods: A total of 47 patients with ischemic stroke and 26 control subjects were recruited. The cases were well-matched to controls for age and sex. Peripheral blood samples from stroke patients were obtained between 12-24 hours after the stroke. Serum levels of hsCRP were determined by chemoluminescence assay. Results: The mean serum levels of hsCRP were found to be significantly higher in patients (3.12 +/- 4.4 mg/dL) than controls (0.39 +/- 0.6 mg/dL, p=0.0001). The level of hsCRP was above the risk limit in 39 patients (83.0%) and 7 controls (26.9%). The hsCRP values were not related to the presence of other vascular risk factors, except for cholesterol level. The correlation analysis of hsCRP revealed a linear correlation with death within six months and the presence of hypertension. Conclusions: Our results suggest that elevated serum hsCRP levels may be an indicator of fatal outcome in first-time stroke patients.en_US
dc.identifier.endpageCR544en_US
dc.identifier.issn1643-3750
dc.identifier.issue11en_US
dc.identifier.pmid16258400en_US
dc.identifier.scopus2-s2.0-28144443883en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpageCR540en_US
dc.identifier.urihttps://hdl.handle.net/11616/94170
dc.identifier.volume11en_US
dc.identifier.wosWOS:000233423100016en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInt Scientific Information, Incen_US
dc.relation.ispartofMedical Science Monitoren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectischemic strokeen_US
dc.subjecthsCRPen_US
dc.subjectrisk factorsen_US
dc.subjectprognosisen_US
dc.titleC-reactive protein is an indicator for fatal outcomes in first-time stroke patientsen_US
dc.typeArticleen_US

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