Synthesis, characterization, crystal structure, and antimicrobial studies of 2-morpholinoethyl-substituted benzimidazolium salts and their silver(I)-N-heterocyclic carbene complexes

Basit Öğe Kaydı
dc.authoridAygün, Muhittin/0000-0001-9670-9062
dc.authoridAygün, Muhittin/0000-0001-9670-9062
dc.authoridKUTLU, Turkan/0000-0002-1501-9930
dc.authoridAktaş, Aydın/0000-0001-8496-6782
dc.authoridYıldırım, Işıl/0000-0002-3027-6054
dc.authorwosidGök, Yetkin/AAA-5669-2021
dc.authorwosidAygün, Muhittin/P-3605-2019
dc.authorwosidAygün, Muhittin/E-9590-2011
dc.authorwosidBarut Celepci, Duygu/M-6189-2017
dc.authorwosidKUTLU, Turkan/ABI-2589-2020
dc.authorwosidAktaş, Aydın/J-6194-2019
dc.authorwosidYıldırım, Işıl/AAJ-6588-2020
dc.contributor.authorYildirim, Isil
dc.contributor.authorAktas, Aydin
dc.contributor.authorCelepci, Duygu Barut
dc.contributor.authorKirbag, Sevda
dc.contributor.authorKutlu, Turkan
dc.contributor.authorGok, Yetkin
dc.contributor.authorAygun, Muhittin
dc.date.accessioned2024-08-04T20:43:12Z
dc.date.available2024-08-04T20:43:12Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis article describes synthesis of N-morpholinoethylbenzimidazole (1), 2-morpholinoethyl-substituted benzimidazolium salts (NHC precursors, 2a-c), and their Ag(I) N-heterocyclic carbene (NHC) complexes (3a-c). All compounds were characterized by H-1 and C-13 Nuclear Magnetic Resonance (NMR), Fourier Transform Infrared Spectroscopy (FTIR), and elemental analysis, and their antimicrobial effects examined. The molecular structure of the NHC precursor 2a (1) was established by single-crystal X-ray diffraction analysis. Minimum Inhibition Concentration (MIC) values were determined to evaluate their antimicrobial activity against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus bacterial strains and Candida albicans fungal species. All tested samples were compared with silver nitrate. All the compounds exhibited strong antimicrobial activity.en_US
dc.description.sponsorshipInonu University, Research Project Unit [I.U.A.F:2011/25]; Dokuz Eylul University [2010.KB.FEN.13]en_US
dc.description.sponsorshipThe authors are grateful for financial support provided by Inonu University, Research Project Unit (project no. I.U.A.F:2011/25), and support for NMR and elemental analyses provided by Inonu University Central Research Laboratory. The authors acknowledge Dokuz Eylul University for use of the Agilent Xcalibur Eos diffractometer (purchased under university research grant no. 2010.KB.FEN.13). CCDC 1499376 contains the supplementary crystallographic data for 2a1. Copies of the data can be obtained free of charge at http://www.ccdc.cam.ac.uk/conts/retrieving.html or from the Cambridge Crystallographic Data Centre, 12, Union Road, Cambridge, CB2 1EZ, UK. fax: (+44) 1223-336-033, email: deposit@ccdc.cam.ac.uk.en_US
dc.identifier.doi10.1007/s11164-017-2995-3
dc.identifier.endpage6393en_US
dc.identifier.issn0922-6168
dc.identifier.issn1568-5675
dc.identifier.issue11en_US
dc.identifier.scopus2-s2.0-85020705223en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage6379en_US
dc.identifier.urihttps://doi.org/10.1007/s11164-017-2995-3
dc.identifier.urihttps://hdl.handle.net/11616/97857
dc.identifier.volume43en_US
dc.identifier.wosWOS:000412748900022en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofResearch on Chemical Intermediatesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectN-Heterocyclic carbeneen_US
dc.subjectAg-NHC complexesen_US
dc.subjectMorpholineen_US
dc.subjectAntimicrobial activityen_US
dc.subjectAntibioticen_US
dc.titleSynthesis, characterization, crystal structure, and antimicrobial studies of 2-morpholinoethyl-substituted benzimidazolium salts and their silver(I)-N-heterocyclic carbene complexesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu