Ketamine or alfentanil administration prior to propofol anaesthesia: the effects on ProSeal™ laryngeal mask airway insertion conditions and haemodynamic changes in children

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dc.authoridbegeç, zekine/0000-0002-9506-1871
dc.authoridErdil, Feray Akgül/0000-0002-7544-3717
dc.authorwosidbegeç, zekine/ABI-5491-2020
dc.authorwosidErdil, Feray Akgül/ABI-2474-2020
dc.contributor.authorBegec, Z.
dc.contributor.authorDemirbilek, S.
dc.contributor.authorOnal, D.
dc.contributor.authorErdil, F.
dc.contributor.authorIlksen Toprak, H.
dc.contributor.authorOzcan Ersoy, M.
dc.date.accessioned2024-08-04T20:31:08Z
dc.date.available2024-08-04T20:31:08Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis study was designed to compare the effects of ketamine and alfentanil administered prior to induction of anaesthesia with propofol, on the haemodynamic changes and ProSeal laryngeal mask airway((R)) (PLMA) insertion conditions in children. Eighty children, aged between 3-132 months, were randomly allocated to receive either alfentanil 20 mu g.kg(-1) (alfentanil group) or ketamine 0.5 mg.kg(-1) (ketamine group) before induction of anaesthesia. Ninety seconds following the administration of propofol 4 mg.kg(-1), a PLMA was inserted. In the ketamine group, heart rate and mean arterial pressure were higher during the study period compared with the alfentanil group (p < 0.05). The time for the return of spontaneous ventilation was prolonged in the alfentanil group (p = 0.004). In conclusion, we found that the administration of ketamine 0.5 mg.kg(-1) with propofol 4 mg.kg(-1) preserved haemodynamic stability, and reduced the time to the return of spontaneous ventilation, compared with alfentanil 20 mu g.kg(-1) during PLMA placement. In addition, the conditions for insertion of the PLMA with ketamine were similar to those found with alfentanil.en_US
dc.identifier.doi10.1111/j.1365-2044.2008.05782.x
dc.identifier.endpage286en_US
dc.identifier.issn0003-2409
dc.identifier.issn1365-2044
dc.identifier.issue3en_US
dc.identifier.pmid19302641en_US
dc.identifier.scopus2-s2.0-61749087435en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage282en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-2044.2008.05782.x
dc.identifier.urihttps://hdl.handle.net/11616/94758
dc.identifier.volume64en_US
dc.identifier.wosWOS:000263242800009en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAnaesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectInductionen_US
dc.subjectFentanylen_US
dc.titleKetamine or alfentanil administration prior to propofol anaesthesia: the effects on ProSeal™ laryngeal mask airway insertion conditions and haemodynamic changes in childrenen_US
dc.typeArticleen_US

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