Remineralization effect of three different agents on initial caries and erosive lesions: a micro-computed tomography and scanning electron microscopy analysis

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dc.authoridAkkuc, Sibel/0000-0003-4504-6988
dc.authoridKeleş, Ali/0000-0003-2835-767X
dc.authoridDuruk, Gulsum/0000-0002-6756-6637
dc.authorwosidAkkuc, Sibel/ABH-6464-2020
dc.authorwosidKeleş, Ali/J-5897-2015
dc.contributor.authorAkkuc, Sibel
dc.contributor.authorDuruk, Gulsum
dc.contributor.authorKeles, Ali
dc.date.accessioned2024-08-04T20:53:26Z
dc.date.available2024-08-04T20:53:26Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackgroundThis study aimed to investigate the remineralization efficiency of Sensodyne Promine containing Sodium flouride (NaF), GC Tooth Mousse containing CPP-ACP, and Agarta herbal toothpaste on initial caries and erosion using micro-computed tomography (CT) and scanning electron microscopy (SEM).MethodsForty-five third-molar teeth for micro-CT were divided into three main groups after initial scans (T-1) were completed. Artificial caries lesions were created with the demineralization cycle (group 1, n = 15) and artificial erosion lesions were created with orange juice (group 2, n = 15) and Cola (group 3, n = 15), and second scans (T-2) were performed. The groups were divided into three subgroups within themselves. Sensodyne Promine toothpaste (subgroup 1a, 2a, 3a), GC Tooth Mousse topical cream (subgroup 1b, 2b, 3b), and Agarta herbal toothpaste (subgroup 1c, 2c, 3c) were applied using soft-tipped brushes for 2 min, twice per day for 15 days, and then a third scan (T-3) was performed. Mineral density, surface area, and lesion volume and depth were calculated using micro-CT. Changes in the surface morphology of the teeth were examined using SEM in 13 samples representing each group, subgroup, and healthy enamel. In the analysis of the data obtained from the scans performed at three different times (T-1, T-2, T-3), one-way analysis of variance (ANOVA) with the post-hoc Tukey test, repeated measures ANOVA with the post-hoc Bonferroni test, and paired sample t-test analyses were used.ResultsAll three agents caused a statistically significant increase in mineral density, and a decrease in surface area and lesion volume and depth (p < 0.05). There was no statistically significant difference between the groups in remineralization efficiency (p > 0.05). A statistically significant difference was found between the groups regarding the mineral density of the tissue that increased after remineralization (NaF > CPP-ACP > He; p < 0.05).ConclusionThe remineralization efficacy of herbal toothpaste as an alternative to NaF and CPP-ACP was found to be successful.en_US
dc.description.sponsorshipScientific Research Foundation of Inonu University [TDH 2021/2575]en_US
dc.description.sponsorshipAcknowledgementsThe authors would like to thank the Scientific Research Foundation of Inonu University for financially supporting this study (TDH 2021/2575).en_US
dc.identifier.doi10.1186/s12903-023-02805-6
dc.identifier.issn1472-6831
dc.identifier.issue1en_US
dc.identifier.pmid36797742en_US
dc.identifier.scopus2-s2.0-85148260484en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1186/s12903-023-02805-6
dc.identifier.urihttps://hdl.handle.net/11616/101176
dc.identifier.volume23en_US
dc.identifier.wosWOS:000935906900001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofBmc Oral Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMicro-CTen_US
dc.subjectSEMen_US
dc.subjectErosionen_US
dc.subjectDemineralizationen_US
dc.subjectRemineralizationen_US
dc.subjectFluorideen_US
dc.subjectHerbalen_US
dc.subjectCPP-ACPen_US
dc.subjectToothpasteen_US
dc.titleRemineralization effect of three different agents on initial caries and erosive lesions: a micro-computed tomography and scanning electron microscopy analysisen_US
dc.typeArticleen_US

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