Efficacy of stereotactic radiotherapy as salvage treatment for recurrent malignant gliomas

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dc.authoridOlmezoglu, Ali/0000-0002-7809-9819
dc.authorwosidOlmezoglu, Ali/M-7932-2017
dc.contributor.authorEkici, Kemal
dc.contributor.authorOzsekee, Naciye
dc.contributor.authorMayadagli, Alpaslan
dc.contributor.authorKocak, Mihriban Erdogan
dc.contributor.authorOlmezoglu, Ali
dc.date.accessioned2024-08-04T20:40:02Z
dc.date.available2024-08-04T20:40:02Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: To evaluate the efficacy and toxicity of CyberKnife stereotactic radiotherapy (SRT) for recurrent glial tumors previously treated with high-dose radiotherapy. Methods: CyberKnife SRT was performed in 37 patients with recurrent glial tumors who presented to our hospital between January 2007 and March 2012. The patients were subjected to a dose ranging from 20 to 28 Gy using the CyberKnife system with an average of two fractions. The median follow-up duration after SRT was 14 months (range 1.8-57). Results: The median survival time of the patients after recurrence was 22.3 months (95% confidence interval/95% Cl 12.5-32). The median survival times of the high- and low-grade patients were 29 and 19 months, respectively. No significant toxicity due to radiation was noticed during the follow-up period. No factor influencing mortality was found in either the univari ate or multivariate analysis.. Conclusion: SRT using CyberKnife is an effective and safe treatment choice for recurrent glial tumors. SRT achieves a more favorable outcome in the treatment of recurrent tumors, particularly in high-grade onesen_US
dc.identifier.endpage1034en_US
dc.identifier.issn1107-0625
dc.identifier.issn2241-6293
dc.identifier.issue4en_US
dc.identifier.pmid25536612en_US
dc.identifier.scopus2-s2.0-84921895244en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1029en_US
dc.identifier.urihttps://hdl.handle.net/11616/96668
dc.identifier.volume19en_US
dc.identifier.wosWOS:000347742000026en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherImprimatur Publicationsen_US
dc.relation.ispartofJournal of Buonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCyberKnifeen_US
dc.subjectglial tumorsen_US
dc.subjectrecurrenceen_US
dc.subjectstereotactic radiosurgeryen_US
dc.titleEfficacy of stereotactic radiotherapy as salvage treatment for recurrent malignant gliomasen_US
dc.typeArticleen_US

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