Inhibitory effect of bioactive compounds derived from freeze-dried paraprobiotic of Pediococcus acidilactici against food-borne pathogens: In-vitro and food model studies

Basit Öğe Kaydı
dc.authoridKanmaz, Hilal/0000-0002-9363-8454
dc.authoridHayaloglu, Ali Adnan/0000-0002-4274-2729
dc.authoridİncili, Gökhan Kürşad/0000-0003-1178-3365
dc.authoridtekin, ali/0000-0001-5258-1714
dc.authoridKaya, Busra/0000-0001-8207-9741
dc.authorwosidKanmaz, Hilal/AAA-7257-2021
dc.authorwosidHayaloglu, Ali Adnan/ABF-7063-2020
dc.authorwosidTekin, Ali/V-9059-2018
dc.authorwosidKaya, Büşra/KOD-5584-2024
dc.authorwosidİncili, Gökhan Kürşad/W-3869-2018
dc.contributor.authorIncili, Gokhan Kursad
dc.contributor.authorAkgol, Muzeyyen
dc.contributor.authorKaratepe, Pinar
dc.contributor.authorKanmaz, Hilal
dc.contributor.authorKaya, Busra
dc.contributor.authorTekin, Ali
dc.contributor.authorHayaloglu, Ali Adnan
dc.date.accessioned2024-08-04T20:53:45Z
dc.date.available2024-08-04T20:53:45Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIt was aimed to assess the antimicrobial potential of lyophilized/freeze-dried paraprobiotic (LP) of P. acidilactici against some food-borne pathogens under in-vitro conditions and food model, and determination of bioactive compounds that contribute to the antimicrobial activity of LP. For this purpose, minimum inhibitory concen-tration (MIC), inhibition zones were determined against Listeria monocytogenes, Salmonella Typhimurium and Escherichia coli O157:H7. The MIC value was 6.25 mg/mL and a 20 & mu;L LP displayed 8.78 to 10.0 mm inhibition zones against these pathogens. In the food matrice challenge, two concentrations of LP (3% and 6%) alone or in combination with EDTA (0.02 M) were added to pathogenic bacteria spiked meatballs, and antimicrobial activity of LP was also determined during refrigerated storage. 6% LP + 0.02 M EDTA treatment provided 1.32 to 3.11 log10 CFU/g reductions in the numbers of these pathogens (P < 0.05). Furthermore, this treatment provided significant reductions on psychrotrophs, TVC, LAB, mold-yeast, and Pseudomonas spp. over the storage (P < 0.05). Regarding characterization results, LP contained contained a wide variety of bioactive compounds, including 5 organic acids (2.15 to 30.64 g/100 g), 19 free amino acids (6.97 to 699.15 mg/100 g), free fatty acids (short-, medium-, and long-chain fatty acids), 15 polyphenols (0.03 to 383.78 mg/100 g), and some volatile compounds such as pyrazines, pyranone and pyrrole derivatives. These bioactive compounds are not only involved in antimicrobial activity but also contribute to the free radical scavenging activity according to the DPPH, ABTS and FRAP assays. In conclusion, the result revealed that the LP improved the chemical and microbiological quality of foods due to containing biologically-active metabolites involved in antimicrobial and antioxidant capacity.en_US
dc.identifier.doi10.1016/j.foodres.2023.113045
dc.identifier.issn0963-9969
dc.identifier.issn1873-7145
dc.identifier.pmid37316034en_US
dc.identifier.scopus2-s2.0-85160550502en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.foodres.2023.113045
dc.identifier.urihttps://hdl.handle.net/11616/101377
dc.identifier.volume170en_US
dc.identifier.wosWOS:001016744500001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofFood Research Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBioactive compoundsen_US
dc.subjectPolyphenolsen_US
dc.subjectOrganic acidsen_US
dc.subjectFreeze-dried paraprobioticen_US
dc.subjectPediococcus acidilacticien_US
dc.titleInhibitory effect of bioactive compounds derived from freeze-dried paraprobiotic of Pediococcus acidilactici against food-borne pathogens: In-vitro and food model studiesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu