QT dispersion in patients with pulmonary embolism

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dc.authoridSen, Nazan/0000-0002-4171-7484
dc.authoridErmis, Hilal/0000-0002-1764-9098
dc.authoridKepez, Alper/0000-0003-3868-3268
dc.authorwosidErmis, Necip/HJP-7061-2023
dc.authorwosidErmis, Necip/A-5184-2018
dc.authorwosidÇUĞLAN, bilal/AAP-8878-2021
dc.authorwosidSen, Nazan/AAI-8947-2021
dc.authorwosidErmis, Hilal/ABI-2900-2020
dc.authorwosidKepez, Alper/A-6204-2018
dc.contributor.authorErmis, Necip
dc.contributor.authorErmis, Hilal
dc.contributor.authorSen, Nazan
dc.contributor.authorKepez, Alper
dc.contributor.authorCuglan, Bilal
dc.date.accessioned2024-08-04T20:32:41Z
dc.date.available2024-08-04T20:32:41Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Various ECG patterns have been associated with acute pulmonary embolism. However, there is no data regarding the association between QT interval measurements and pulmonary embolism. We aimed to investigate the association between QT dispersion and the severity of pulmonary embolism (PE). Methods: One hundred twenty-nine pulmonary embolism patients (mean age 58 +/- 16.5 years) with ECGs obtained within the first 24 hours of hospital admission were included in the study. Patients were classified into low, intermediate and high-risk groups. We retrospectively measured ECG scores; maximum and minimum corrected QT intervals (QTc(max) and QTc(min)) and corrected QT interval dispersion (QTcd) in each risk group of patients. Results: There was an increasing ECG score through from low to high-risk PE [3 (Interquartile Range, IQR: 2), 5 (IQR: 6) and 10 (IQR: 7) p < 0.0001]. QT interval analysis showed that QTcd was higher in high-risk group than in low and intermediate-risk groups (59.5 +/- 23.4, 69.2 +/- 21, 95.9 +/- 33.2, p < 0.001 and p = 0.01, respectively). Patients who died after diagnosis had significantly higher QTcd values at baseline compared with the QTcd values of surviving patients (89.1 +/- 45.5 to 65 +/- 22.9, p = 0.001). The sensitivity of QTcd > 71.5 ms for prediction of mortality was 71% with a specificity of 73% (p = 0.001). We observed a strong correlation between QTcd and ECG score values (r = 0.69, p< 0.001). There was also a correlation between QTcd values and pulmonary artery pressure (PAP) (r = 0.027, p = 0.001) Conclusion: QTcd is significantly increased in high-risk PE patients compared to intermediate and low-risk patients. In addition, QTcd is significantly correlated with ECG score and PAP.r = 0.27, p = 0.05).en_US
dc.identifier.doi10.1007/s00508-010-1491-1
dc.identifier.endpage697en_US
dc.identifier.issn0043-5325
dc.identifier.issn1613-7671
dc.identifier.issue23-24en_US
dc.identifier.pmid21136187en_US
dc.identifier.scopus2-s2.0-78651406680en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage691en_US
dc.identifier.urihttps://doi.org/10.1007/s00508-010-1491-1
dc.identifier.urihttps://hdl.handle.net/11616/95234
dc.identifier.volume122en_US
dc.identifier.wosWOS:000287511700008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Wienen_US
dc.relation.ispartofWiener Klinische Wochenschriften_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPulmonary embolismen_US
dc.subjectelectrocardiogramen_US
dc.subjectQT dispersionen_US
dc.subjectECG scoreen_US
dc.subjectpulmonary artery pressureen_US
dc.titleQT dispersion in patients with pulmonary embolismen_US
dc.typeArticleen_US

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