Patient-controlled Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic Scoliosis

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dc.authoridDurmus, Mahmut/0000-0001-9594-9064
dc.authoridaydogan, mustafa said/0000-0002-7106-1156
dc.authoridOzkan, Ahmet Selim/0000-0002-4543-8853
dc.authoridOZGUL, Ulku/0000-0003-3738-1751
dc.authoridUçar, Muharrem/0000-0002-1232-9829
dc.authoridKorkmaz, Mehmet Fatih/0000-0001-7498-6763
dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X
dc.authorwosidDurmus, Mahmut/ABH-3006-2020
dc.authorwosidaydogan, mustafa said/AAA-2828-2021
dc.authorwosidDurmuş, Mahmut/AAG-3377-2019
dc.authorwosidOzkan, Ahmet Selim/ABH-2918-2020
dc.authorwosidOZGUL, Ulku/ABI-6823-2020
dc.authorwosidErdogan, Mehmet Ali/ABI-7224-2020
dc.authorwosidUçar, Muharrem/ABH-7761-2020
dc.contributor.authorErdogan, Mehmet Ali
dc.contributor.authorOzgul, Ulku
dc.contributor.authorUcar, Muharrem
dc.contributor.authorKorkmaz, Mehmet Fatih
dc.contributor.authorAydogan, Mustafa Said
dc.contributor.authorOzkan, Ahmet Selim
dc.contributor.authorColak, Cemil
dc.date.accessioned2024-08-04T20:42:43Z
dc.date.available2024-08-04T20:42:43Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractStudy Design. A prospective, randomized, double-blinded study. Objective. The aim of this study was to compare the efficacy and side effects of patient-controlled intermittent bolus epidural analgesia (PCIEA) and patient-controlled continuous epidural analgesia (PCCEA) for postoperative pain control in adolescent idiopathic scoliosis. Summary of Background Data. Epidural analgesia is an accepted efficacious and safe procedure for postoperative pain management in scoliosis surgery. However, the PCIEA has not been adequately investigated for postoperative pain control in adolescent idiopathic scoliosis. Methods. Forty-seven patients, 8 to 18 years of age, who were undergoing posterior spinal fusion for idiopathic scoliosis were randomized to either the PCIEA or PCCEA group. An epidural catheter was inserted by a surgeon under direct visualization. The PCIEA group received 0.2 mg/mL of morphine, 0.25 mL/kg of morphine bolus, additional doses of 0.25 mL/kg morphine with a 1-hour lockout given by patient-controlled demand, and no infusion. The PCCEA group received the following: 0.2 mg/mL morphine, an initial morphine loading set at 0.1 mL/kg, followed by a 0.05 mL/kg/h continuous infusion of morphine, and a 0.025 mL/kg bolus dose of morphine. There was a 30-minute lockout interval. The primary outcome was morphine usage. The secondary outcomes were pain score, postoperative nausea and vomiting, and pruritus. Results. Cumulative morphine consumption was lower in the PCIEA group than in the PCCEA group. Both methods provided effective pain control. There were no differences in pain scores between the groups. Postoperative nausea, vomiting, and pruritus were lower in the PCIEA group. Conclusion. The two epidural analgesia techniques studied are both safe and effective methods for postoperative pain control after posterior spinal fusion in idiopathic scoliosis. Nausea, vomiting and pruritus were considerably higher in the PCCEA group. Concerns regarding side effects associated with epidural opioids can be avoided by an intermittent bolus with a relatively lower amount of opioid.en_US
dc.identifier.doi10.1097/BRS.0000000000001937
dc.identifier.endpage886en_US
dc.identifier.issn0362-2436
dc.identifier.issn1528-1159
dc.identifier.issue12en_US
dc.identifier.pmid27792112en_US
dc.identifier.scopus2-s2.0-84992702731en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage882en_US
dc.identifier.urihttps://doi.org/10.1097/BRS.0000000000001937
dc.identifier.urihttps://hdl.handle.net/11616/97553
dc.identifier.volume42en_US
dc.identifier.wosWOS:000403423700013en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofSpineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpain managementen_US
dc.subjectpatient-controlled epidural analgesiaen_US
dc.subjectscoliosisen_US
dc.titlePatient-controlled Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic Scoliosisen_US
dc.typeArticleen_US

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