Dişilerde Varikosei: Rat Modeli
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Dosyalar
Tarih
1999
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turgut Özal Tıp Merkezi Dergisi
Erişim Hakkı
Attribution 3.0 United States
Özet
Kadınlarda varikosei şu anda araştırma konusudur. Geliştirilecek bir hayvan modeli bu konuyla ilgili patolojileri ortaya koymak için uygun bir seçenek oluşturabilir. Bu amaçla Virgin dişi wistar ratlarda ortahat iaparatomi yapılarak soi renal ven bulunup çapı 0.85 mm olacak şekilde kısmi daraltma yapıldı. Bu darlık, metal bir prob ve renal ven etrafına konan 4-0 ipek bir sütür sonrası metal prob alınarak sağlandı. Makroskopik ve mikroskop/k olarak modelimizi araştırdık. Soi ovarian vende ve intraovarian damarlarda belirgin dilatasyon gözlendi. Bu modelin kadın varikoseli patolojik değişikliklerini araştırmak için kolay ve ucuz bir yöntem olduğu sonucuna varıldı.
Female varicocele is a subject of investigation. An animat model of female varicocele may be an option to detect pathoiogies associated with this phenomenon. For this purpose, a midline laparatomy was performed in female wistar rats. The ieft renai vein was identified and partially Ugated to an external diameter of 0.85 mm. A consistent stenosis was achieved by using a 4-0 silk suture, which was Ugated around both renal vein and a metal probe. The probe was removed and the vein was aliovved to expand against the loop of suture. This model was macroscopically and microscopically investigated. Markedty dilated İeft ovarian vein and striking intraovarian venous congestion were observed. It was conduded that this model is an easy and cheap option to investigate female varicocele.
Female varicocele is a subject of investigation. An animat model of female varicocele may be an option to detect pathoiogies associated with this phenomenon. For this purpose, a midline laparatomy was performed in female wistar rats. The ieft renai vein was identified and partially Ugated to an external diameter of 0.85 mm. A consistent stenosis was achieved by using a 4-0 silk suture, which was Ugated around both renal vein and a metal probe. The probe was removed and the vein was aliovved to expand against the loop of suture. This model was macroscopically and microscopically investigated. Markedty dilated İeft ovarian vein and striking intraovarian venous congestion were observed. It was conduded that this model is an easy and cheap option to investigate female varicocele.
Açıklama
Turgut Özal Tıp Merkezi Dergisi.6 (2) :1999. İnönü Üniversitesi, Malatya.
Anahtar Kelimeler
hayvan modeli, kadın varikoseli, pelvik ağrı, Female varicocele, animal model, pelvic pain
Kaynak
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Gokdenız, Remzi ;Özbek, Emin ;Mızrak, Bülent ;Özen, Süleyman ;Turgut Özal Tıp Merkezi Dergisi.6 (2) :1999. İnönü Üniversitesi, Malatya.
