Assessment of left atrial volume and mechanical functions using real-time three-dimensional echocardiography in patients with mitral annular calcification
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish Soc Cardiology
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: Mitral annular calcification (MAC) is degeneration of the fibrous annular ring of the mitral valve. Left atrial (LA) function and volume have been evaluated by many methods; however, none have used real-time three-dimensional echocardiography (RT3DE) in patients with MAC. Our study is the first to evaluate LA volume and mechanical function using RT3DE in patients with MAC. Methods: Our study was a prospective cross-sectional study. In total, 32 patients with echocardiographic evidence of MAC and 30 volunteers without MAC were enrolled in the study. Kolmogorov-Smirnov test, Student's t-test, Mann-Whitney U test, chi-square test, Pearson's correlation test, and multiple linear regression analyses were used in this study. Results: LA diameter was significantly higher in patients with MAC (38.5 +/- 3.8 vs. 31.1 +/- 2.9, p<0.001). Maximum LA volume (49.6 +/- 11.2 vs. 35.6 +/- 2.5, p<0.001), minimum LA volume (23.8 +/- 7.9 vs. 12.6 +/- 2.3, p<0.001), and LA volume index (LAVI) (26.9 +/- 6.1 vs. 20.5 +/- 2.4, p<0.001) were also higher in the MAC group. LAVI was correlated with age (p<0.001), blood urea nitrogen levels (p=0.089), total cholesterol levels (p=0.055), left ventricular systolic myocardial velocity (p=0.048), E/A ratio (p<0.001), and MAC (p<0.001). Multiple linear regression analyses revealed that age (beta=0.390, p<0.001) and MAC (beta=0.527, p<0.001) were independent predictors of LAVI. Conclusion: We found that LA mechanical function was impaired in patients with MAC. Furthermore, age and MAC were independent predictors of increased LAVI according to our RT3DE examination.
Açıklama
Anahtar Kelimeler
mitral annular calcification, left atrial volume index, real-time three-dimensional echocardiography
Kaynak
Anatolian Journal of Cardiology
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
16
Sayı
1
