Metastatic malignant peripheral nerve sheath tumor in neurofibromatosis Type 1: a geriatric patient report

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dc.authorwosidFirat, Cemal/D-1292-2012
dc.contributor.authorFirat, C.
dc.contributor.authorAytekin, A. H.
dc.contributor.authorErbatur, S.
dc.date.accessioned2024-08-04T20:36:11Z
dc.date.available2024-08-04T20:36:11Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractNeurofibromatosis type 1 (NF1) (von Recklinghausen disease) is an autosomal dominantly inherited neurocutaneous disorder which affects many systems like ocular, cutaneous and nervous systems and seen in 1:3500 births. Cardinal diagnostic criteria of NF1 were established in 1987 by National Institutes of Health Consensus. Early diagnosis and the findings of NF1 are unclear in childhood, but with age the clinical symptoms become apparent. NF1 is occasionally associated with mental retardation. In this report, together a review of the literature, we present a quite elderly patient, 79-year-old-man, with NF1 suffering from metastatic malignant peripheral nerve sheath tumor in the axillary lymph node invading the brachial plexus and pleura. Moreover, this enormous metastatic mass had restricted movement of the extremity. He had multiple neurofibromas of different sizes almost covering his entire body, massively. To the best of our knowledge, our patient's malignant peripheral nerve sheath tumor and massive neurofibromatosis is a rare case to present in the eighth decade of life.en_US
dc.identifier.endpage1304en_US
dc.identifier.issn1128-3602
dc.identifier.issue9en_US
dc.identifier.pmid23047517en_US
dc.identifier.scopus2-s2.0-84867922468en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1301en_US
dc.identifier.urihttps://hdl.handle.net/11616/95831
dc.identifier.volume16en_US
dc.identifier.wosWOS:000310405700021en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNeurofibromatosis type 1en_US
dc.subjectMalign peripheral nerve sheath tumoren_US
dc.subjectGeriatricen_US
dc.titleMetastatic malignant peripheral nerve sheath tumor in neurofibromatosis Type 1: a geriatric patient reporten_US
dc.typeArticleen_US

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