The comparison of hemodynamic effects of remifentanil or fentanyl addition to midazolam infusion for total intravenous anesthesia in coronary artery bypass surgery

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dc.authorscopusid6603851680
dc.authorscopusid6603245381
dc.authorscopusid55898201200
dc.authorscopusid55666804700
dc.authorscopusid15073106000
dc.authorscopusid6506222899
dc.contributor.authorKöro?lu A.
dc.contributor.authorGedik E.
dc.contributor.authorGülhaş N.
dc.contributor.authorToprak H.I.
dc.contributor.authorKaraaslan K.
dc.contributor.authorÖzcan Ersoy M.
dc.date.accessioned2024-08-04T20:00:57Z
dc.date.available2024-08-04T20:00:57Z
dc.date.issued2004
dc.departmentİnönü Üniversitesien_US
dc.description.abstractWe aimed to determine the effects of remifentanil or fentanyl infusion with midazolam on response to endotracheal intubation, surgical stimulus and intraoperative hemodynamics in coronary artery bypass surgery. Anesthesia was induced with thiopental sodium 0.5-3 mg kg-1 and 2 ?g kg-1 remifentanil (Group R, n=31), or 15 ?g kg-1 fentanyl (Group F, n=29) in 60 cases included into the study. Anesthesia was maintained with 1 ?g kg-1 min-1 remifentanil in group R or 0.15 ?g kg-1 min-1 fentanyl in group F in addition to the midazolam infusion 0.15 mg kg-1 h-1. Mean arterial pressure (MAP), heart rate (HR) were recorded at 1, 3 and 5 min after intubation and surgical stimulus and 5 min intervals during surgery. Also time to intubation and complications were recorded. Heart rate was lower in group R after anesthesia induction. During opioid infusion both MAP and HR decreased more in group R than F. After skin incision, sternotomy and internal mamarian artery dissection MAP and HR were higher in group F than R. Hypertensive response to sternotomy, skin incision, internal mamarian artery dissection was less in group R than group F. Frequency of hypertension and requirement of nitroglycerin were lower in group R than group F during CPB. We concluded that thiopental sodium with remifentanil or fentanyl in anesthesia induction did not prevent the hypertensive response to intubation. However maintenance with remifentanil and midazolam infusion was more effective in preventing surgical stimuli.en_US
dc.identifier.endpage106en_US
dc.identifier.issn1300-0578
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-17544401508en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage101en_US
dc.identifier.urihttps://hdl.handle.net/11616/91140
dc.identifier.volume12en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofAnestezi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCoronary artery bypass surgeryen_US
dc.subjectFentanylen_US
dc.subjectMidazolamen_US
dc.subjectRemifentanilen_US
dc.titleThe comparison of hemodynamic effects of remifentanil or fentanyl addition to midazolam infusion for total intravenous anesthesia in coronary artery bypass surgeryen_US
dc.title.alternativeKoroner Arter Bypass Cerrahisinde Total ? Intravenöz Anestezi: Midazolamla Birlikte Remifentanil veya Fentanil ? Infüzyonunun Hemodinamik Etkilerinin Karşilaştirilmasien_US
dc.typeArticleen_US

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