Autonomic nervous system involvement in Behçet's disease: A pupillometric study

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dc.authorscopusid6701587135
dc.authorscopusid6701335627
dc.authorscopusid7801560529
dc.authorscopusid6506223480
dc.authorscopusid7006785766
dc.contributor.authorBayramlar H.
dc.contributor.authorHep?en I.F.
dc.contributor.authorU?uralp M.
dc.contributor.authorBölük A.
dc.contributor.authorÖzcan C.
dc.date.accessioned2024-08-04T20:00:46Z
dc.date.available2024-08-04T20:00:46Z
dc.date.issued1998
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to elucidate whether autonomic nervous system dysfunction exists in patients with Behçet's disease by pupillometric tests. Thirty-one patients with Behçet's disease with a mean age of 41.3 years (range 21-64) and 41 control subjects with a mean age of 39.5 years (range 18-66) were selected for the study. To test the autonomic nervous system, four pupillometric techniques were used: pupil cycle time (PCT), dark-adapted pupil size (DAPS), 0.05% pilocarpine drop test, and 1% phenylephrine drop test. In all four tests, there were significant differences between the patients and controls. Mean PCTs were 1,156 ms (range 856-1,560 ms) and 919 ms (range 650-1,261 ms) in the patients and controls, respectively (p < 0.0001). The mean DAPS was 0.45 (range 0.31-0.66) in the patients, whereas it was 0.56 (range 0.42-0.67) in controls (p < 0.001). Iris sensitivity to both 0.05% pilocarpine and 1% phenylephrine showed significant differences between patients and controls, respectively (p < 0.05, p < 0.05). Among all four tests, only 0.05% pilocarpine sensitivity was correlated with the duration of Behçet's disease (p < 0.05). The results suggest that the autonomic nervous system innervating the iris is affected in Behçet's disease. This involvement may be due to the vasculitic nature of Behçet's disease. © 1998 Lippincott Williams & Wilkins,.en_US
dc.identifier.endpage186en_US
dc.identifier.issn1070-8022
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-0344015748en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage182en_US
dc.identifier.urihttps://hdl.handle.net/11616/90983
dc.identifier.volume18en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Neuro-Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAutonomic nervous functionen_US
dc.subjectBehçet's diseaseen_US
dc.subjectPupilen_US
dc.subjectPupillometryen_US
dc.titleAutonomic nervous system involvement in Behçet's disease: A pupillometric studyen_US
dc.typeArticleen_US

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