Propolis Prevents the Effects of Chronic Alcohol Intake on Ocular Tissues
dc.authorid | Emre, Sinan/0000-0002-9788-3895; | |
dc.authorwosid | Dogan, Zumrut yılmaz/V-5131-2018 | |
dc.authorwosid | Emre, Sinan/T-5643-2019 | |
dc.authorwosid | Ozturk, Feral/A-2678-2016 | |
dc.contributor.author | Emre, Sinan | |
dc.contributor.author | Yilmaz, Zuemruet | |
dc.contributor.author | Ozturk, Feral | |
dc.contributor.author | Emre, M. Hanifi | |
dc.date.accessioned | 2024-08-04T20:31:16Z | |
dc.date.available | 2024-08-04T20:31:16Z | |
dc.date.issued | 2009 | |
dc.department | İnönü Üniversitesi | en_US |
dc.description.abstract | Aim: This study is designed to investigate the protective effects of propolis in ocular tissues against chronic alcohol exposure. Material and Method: Wistar albino rats were used in this study. Rats were divided into 4 groups, and each group was fed a special liquid diet which contained an equal amount of calories. The control group was fed the liquid special diet without alcohol and propolis. We added propolis (150 mg/kg) to the diet of the second group. The diet of the third group contained alcohol, the concentration of which was increased progressively. The fourth group was fed a diet including propolis and alcohol. To counterbalance caloric intake, we decreased the amount of glucose in the special liquid diet for groups 3 and 4. At the end of 30 days, the animals were sacrificed and samples were kept at -80 degrees C until evaluation. Specimens were investigated by light microscopy for morphology and morphometry. Results: In the histological investigation of ocular tissues, alcohol caused an increase in thickness of the cornea and corneal epithelium compared to the control group (p < 0.05). This incremental tendency was significantly reduced by propolis, and values were very close to those of the control group (p > 0.05). Alcohol did not cause any significant alteration of rat retinal thickness. Conclusion: This study showed that propolis is highly effective against corneal edema secondary to chronic alcohol intake. Copyright (C) 2009 S. Karger AG, Basel | en_US |
dc.identifier.doi | 10.1159/000229029 | |
dc.identifier.endpage | 151 | en_US |
dc.identifier.issn | 0030-3747 | |
dc.identifier.issue | 3 | en_US |
dc.identifier.pmid | 19628955 | en_US |
dc.identifier.scopus | 2-s2.0-67651000176 | en_US |
dc.identifier.scopusquality | N/A | en_US |
dc.identifier.startpage | 147 | en_US |
dc.identifier.uri | https://doi.org/10.1159/000229029 | |
dc.identifier.uri | https://hdl.handle.net/11616/94838 | |
dc.identifier.volume | 42 | en_US |
dc.identifier.wos | WOS:000271535500006 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | Karger | en_US |
dc.relation.ispartof | Ophthalmic Research | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Chronic alcohol intake | en_US |
dc.subject | Keratopathy | en_US |
dc.subject | Propolis | en_US |
dc.title | Propolis Prevents the Effects of Chronic Alcohol Intake on Ocular Tissues | en_US |
dc.type | Article | en_US |