Propolis Prevents the Effects of Chronic Alcohol Intake on Ocular Tissues

dc.authoridEmre, Sinan/0000-0002-9788-3895;
dc.authorwosidDogan, Zumrut yılmaz/V-5131-2018
dc.authorwosidEmre, Sinan/T-5643-2019
dc.authorwosidOzturk, Feral/A-2678-2016
dc.contributor.authorEmre, Sinan
dc.contributor.authorYilmaz, Zuemruet
dc.contributor.authorOzturk, Feral
dc.contributor.authorEmre, M. Hanifi
dc.date.accessioned2024-08-04T20:31:16Z
dc.date.available2024-08-04T20:31:16Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: This study is designed to investigate the protective effects of propolis in ocular tissues against chronic alcohol exposure. Material and Method: Wistar albino rats were used in this study. Rats were divided into 4 groups, and each group was fed a special liquid diet which contained an equal amount of calories. The control group was fed the liquid special diet without alcohol and propolis. We added propolis (150 mg/kg) to the diet of the second group. The diet of the third group contained alcohol, the concentration of which was increased progressively. The fourth group was fed a diet including propolis and alcohol. To counterbalance caloric intake, we decreased the amount of glucose in the special liquid diet for groups 3 and 4. At the end of 30 days, the animals were sacrificed and samples were kept at -80 degrees C until evaluation. Specimens were investigated by light microscopy for morphology and morphometry. Results: In the histological investigation of ocular tissues, alcohol caused an increase in thickness of the cornea and corneal epithelium compared to the control group (p < 0.05). This incremental tendency was significantly reduced by propolis, and values were very close to those of the control group (p > 0.05). Alcohol did not cause any significant alteration of rat retinal thickness. Conclusion: This study showed that propolis is highly effective against corneal edema secondary to chronic alcohol intake. Copyright (C) 2009 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000229029
dc.identifier.endpage151en_US
dc.identifier.issn0030-3747
dc.identifier.issue3en_US
dc.identifier.pmid19628955en_US
dc.identifier.scopus2-s2.0-67651000176en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage147en_US
dc.identifier.urihttps://doi.org/10.1159/000229029
dc.identifier.urihttps://hdl.handle.net/11616/94838
dc.identifier.volume42en_US
dc.identifier.wosWOS:000271535500006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofOphthalmic Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic alcohol intakeen_US
dc.subjectKeratopathyen_US
dc.subjectPropolisen_US
dc.titlePropolis Prevents the Effects of Chronic Alcohol Intake on Ocular Tissuesen_US
dc.typeArticleen_US

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