The role of brain natriuretic peptide in the prediction of cardiac performance in coronary artery bypass grafting

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dc.authoridAlat, Ilker/0000-0003-1860-7620
dc.authoridYagdi, Tahir/0000-0001-6282-2489
dc.authorwosidAlat, Ilker/AAQ-6262-2021
dc.authorwosidYagdi, Tahir/B-3226-2018
dc.contributor.authorSaribulbul, O
dc.contributor.authorAlat, I
dc.contributor.authorCoskun, S
dc.contributor.authorApaydin, AZ
dc.contributor.authorYagdi, T
dc.contributor.authorKiliccioglu, M
dc.contributor.authorAlayunt, EA
dc.date.accessioned2024-08-04T20:13:32Z
dc.date.available2024-08-04T20:13:32Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe relationship between brain natriuretic peptide and cardiopulmonary bypass has not been examined sufficiently In this study, we prospectively examined brain natriuretic peptide levels in the plasma of 26 patients undergoing coronary artery bypass grafting. Brain natriuretic peptide measurements were carried out at 4 times: preoperatively, 3 hours after institution of cross-clamping, 24 hours after institution of cross-clamping, and on the 5th postoperative day. In addition, we measured individual variables and compared them to brain natriuretic peptide levels. Mean preoperative brain natriuretic peptide levels were significantly higher in patients with histories of myocardial infarction (P = 0.0047) and heart failure (ejection fraction less than or equal to0.40) (P = 0.0001). There was a significant correlation between preoperative brain natriuretic peptide levels and cross-clamp times (P = 0.028), and an inverse correlation between those levels and preoperative cardiac indices (P = 0.001). The preoperative brain natriuretic peptide level also correlated inversely with left ventricular ejection fraction before (P = 0.001) and 5 days after (P = 0.01) operation. When the Clinical Severity Scoring System was applied, preoperative brain natriuretic peptide plasma concentrations in 19 patients with risk scores of 0-2 were significantly lower than in the 7 patients whose risk scores were 3-6 (P = 0.006). There was also a significant relationship between preoperative brain natriuretic peptide plasma concentrations and the postoperative requirement for inotropic agents (P = 0.027). This study suggests that plasma brain natriuretic peptide concentration could be one of the predictors of risk in patients undergoing coronary artery bypass grafting.en_US
dc.identifier.endpage304en_US
dc.identifier.issn0730-2347
dc.identifier.issue4en_US
dc.identifier.pmid14677740en_US
dc.identifier.scopus2-s2.0-0345060324en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage298en_US
dc.identifier.urihttps://hdl.handle.net/11616/93688
dc.identifier.volume30en_US
dc.identifier.wosWOS:000187014500008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTexas Heart Insten_US
dc.relation.ispartofTexas Heart Institute Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcardiopulmonary bypassen_US
dc.subjectcoronary artery bypassen_US
dc.subjectnatriuretic peptide, brainen_US
dc.subjectnerve tissue proteins/blooden_US
dc.subjectpredictive value of testsen_US
dc.subjectprospective studiesen_US
dc.titleThe role of brain natriuretic peptide in the prediction of cardiac performance in coronary artery bypass graftingen_US
dc.typeArticleen_US

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