Increased frequency of restless legs syndrome in atopic dermatitis

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dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X
dc.authoridHalisdemir, Nurhan/0000-0003-2151-7917
dc.authoridÇİÇEK, DEMET/0000-0001-8405-7730
dc.authorwosidÇOLAK, CEMİL/ABI-3261-2020
dc.authorwosidHalisdemir, Nurhan/W-5015-2018
dc.authorwosidÇİÇEK, DEMET/V-9829-2018
dc.contributor.authorCicek, D.
dc.contributor.authorHalisdemir, N.
dc.contributor.authorDertioglu, S. B.
dc.contributor.authorBerilgen, M. S.
dc.contributor.authorOzel, S.
dc.contributor.authorColak, C.
dc.date.accessioned2024-08-04T20:36:00Z
dc.date.available2024-08-04T20:36:00Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground. Restless legs syndrome (RLS) is characterized by an unpleasant sensation in the legs, which is difficult to describe, but produces an urge to move the legs frequently. Aim. To assess the prevalence and severity of RLS in patients with atopic dermatitis (AD) and patients with psoriasis, and to investigate the factors potentially associated with RLS. Methods. In total, 253 people were enrolled (120 with AD, 50 with psoriasis and 83 healthy controls). A diagnosis of RLS was made according to the criteria of the International RLS Study Group (IRLSSG), and severity was assessed using the IRLSSG severity scale. Results. RLS was significantly more common in patients with AD (40.8%) than in patients with psoriasis (18.0%) or in controls (10.8%) (P < 0.01 and P < 0.001, respectively). Prevalence of RLS was higher in patients with active AD than in those with inactive AD (55.3% vs. 23.6%) or controls. There was a significant difference in RLS prevalence between patients with active and those with iactive AD, between patients with active AD and healthy controls, between patients with active AD and patients with psoriasis, and between patients with inactive AD and healthy controls (P < 0.001, P < 0.001, P < 0.001, P = 0.04, respectively). There was no significant difference in RLS prevalence between patients with active AD and patients with psoriasis, or between patients with psoriasis and healthy controls (P > 0.05). Of patients who were positive for RLS, 56.9% had a family history of atopy and 40.3% had a family history of RLS, and there was a significant relationship between the presence of RLS and family history of atopy or RLS (P < 0.001 for both). Conclusions. RLS is common in patients with AD, particularly in those with active disease.en_US
dc.identifier.doi10.1111/j.1365-2230.2012.04356.x
dc.identifier.endpage476en_US
dc.identifier.issn0307-6938
dc.identifier.issn1365-2230
dc.identifier.issue5en_US
dc.identifier.pmid22712855en_US
dc.identifier.scopus2-s2.0-84862881654en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage469en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-2230.2012.04356.x
dc.identifier.urihttps://hdl.handle.net/11616/95701
dc.identifier.volume37en_US
dc.identifier.wosWOS:000305509800002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofClinical and Experimental Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectClinical Characteristicsen_US
dc.subjectPrevalenceen_US
dc.subjectEpidemiologyen_US
dc.subjectBupropionen_US
dc.subjectPsoriasisen_US
dc.subjectValidationen_US
dc.subjectPregnancyen_US
dc.subjectSymptomsen_US
dc.subjectQualityen_US
dc.subjectDiseaseen_US
dc.titleIncreased frequency of restless legs syndrome in atopic dermatitisen_US
dc.typeArticleen_US

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