Abo-Incompatible Liver Transplantation in Acute and Acute-On-Chronic Liver Failure

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dc.authoridErsan, Veysel/0000-0002-1510-0288
dc.authoridBayindir, Yasar/0000-0003-3930-774X
dc.authoridYILMAZ, Mehmet/0000-0002-5710-5263
dc.authoridKutlu, Ramazan/0000-0001-7941-7025
dc.authoridKutlu, Ramazan/0000-0001-7941-7025
dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authorwosidErsan, Veysel/AAB-9595-2020
dc.authorwosidKayaalp, Cuneyt/AAH-1764-2021
dc.authorwosidBayindir, Yasar/T-1523-2017
dc.authorwosidYILMAZ, Mehmet/HKM-4739-2023
dc.authorwosidKutlu, Ramazan/B-1624-2016
dc.authorwosidKutlu, Ramazan/AAE-5219-2020
dc.authorwosidYilmaz, Mehmet/AAF-6095-2021
dc.contributor.authorYilmaz, Sezai
dc.contributor.authorAydin, Cemalettin
dc.contributor.authorBurakIsik
dc.contributor.authorKayaalp, Cuneyt
dc.contributor.authorYilmaz, Mehmet
dc.contributor.authorAra, Cengiz
dc.contributor.authorKutlu, Ramazan
dc.date.accessioned2024-08-04T20:37:52Z
dc.date.available2024-08-04T20:37:52Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground/Aims: ABO-incompatible (ABO-I) liver transplantation (LTx) may be mandatory in urgent conditions such as acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) when deceased donor (DD) is unavailable or living donor (LD) selection is limited. This study specifically addresses the problem of urgent ABO-I LTx in critically ill adult patients having ALF or severely decompensated end-stage liver disease. Methodology: This series included 16 patients, 10 underwent ABO-I LD LTx and 6 underwent 7 ABO-I DD LTx. Multiple sessions of plasmapheresis reduced isoaglutinin titres to 1/16 or below, before and after LTx. Results: Mean follow-up period was 10.37 months (1 to 38). Median for MELD scores was 22.5 (17 to 30). Median survival was 9 months and mean survival was 19.5 months. Hospital mortality was 3 (18.7%). Two patients died due to small for size graft syndrome and cerebrovascular bleeding respectively. Hepatic artery thrombosis developed in 3 patients. Two of them died at postoperative 4th and 9th months. Third patient is still alive with hepatic necrosis problem. Conclusions: ABO-I LTx remains an important and unavoidable therapeutic option in adult patients with ALF or ACLF and urgent need for an allograft without the possibility to allocate a blood group compatible liver graft.en_US
dc.identifier.doi10.5754/hge11289
dc.identifier.endpage1193en_US
dc.identifier.issn0172-6390
dc.identifier.issue125en_US
dc.identifier.pmid23478144en_US
dc.identifier.scopus2-s2.0-84885721025en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1189en_US
dc.identifier.urihttps://doi.org/10.5754/hge11289
dc.identifier.urihttps://hdl.handle.net/11616/96237
dc.identifier.volume60en_US
dc.identifier.wosWOS:000330327700044en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherH G E Update Medical Publishing S Aen_US
dc.relation.ispartofHepato-Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectABO incompatibleen_US
dc.subjectAcuteen_US
dc.subjectAcute-on-chronicen_US
dc.subjectLiver failureen_US
dc.subjectLiver transplantationen_US
dc.titleAbo-Incompatible Liver Transplantation in Acute and Acute-On-Chronic Liver Failureen_US
dc.typeArticleen_US

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