Determination of trace elements in rat organs implanted with endodontic repair materials by ICP-MS

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dc.authoridsimsek, neslihan/0000-0003-1142-9016
dc.authoridBulut, Elcin Tekin/0000-0001-8382-9065
dc.authorwosidsimsek, neslihan/ABF-1071-2020
dc.authorwosidalan, hilal/ABH-9301-2020
dc.authorwosidBulut, Elcin Tekin/O-9884-2015
dc.contributor.authorSimsek, Neslihan
dc.contributor.authorBulut, Eclin Tekin
dc.contributor.authorAhmetoglu, Fuat
dc.contributor.authorAlan, Hilal
dc.date.accessioned2024-08-04T20:41:26Z
dc.date.available2024-08-04T20:41:26Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTo investigate the levels of seven elements using an inductively coupled plasma-mass spectrometry (ICP-MS) method in rat organs after the implantation of Micro Mega Mineral Trioxide Aggregate (MM-MTA), Bioaggregate (BA) and Biodentine (BD) materials. MM-MTA, BA and BD were implanted into the subcutaneous tissue of 15 Wistar albino rats; three control animals had no operation. After 45 days, the rats were sacrificed and their brains, kidneys and livers were removed. The ICP-MS analysis was used to determine trace elements. Data were analysed using the Kruskal-Wallis and Connover post hoc tests. There was no significant difference between the control groups and the MM-MTA, BA and BD groups according to the concentration of aluminum, calcium, arsenic and lead in the rats' organs. Beryllium was not detected in all tissue samples. Chromium levels of these materials were higher than the control group in brain and kidney samples (P = 0.038 and P = 0.037); magnesium levels were higher than the control group in kidney and liver samples (P = 0.030 and P = 0.008). MM-MTA, BA and BD were nontoxic according to trace element levels in brain, kidney and liver samples of rats. Further investigation is required to understand the systemic effects of these materials.en_US
dc.description.sponsorshipScientific Research Projects Unit [2013/117]; Inonu University/Turkeyen_US
dc.description.sponsorshipThis project was supported by Inonu University/Turkey, Scientific Research Projects Unit (2013/117).en_US
dc.identifier.doi10.1007/s10856-015-5663-4
dc.identifier.issn0957-4530
dc.identifier.issn1573-4838
dc.identifier.issue3en_US
dc.identifier.pmid26758893en_US
dc.identifier.scopus2-s2.0-84954319392en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1007/s10856-015-5663-4
dc.identifier.urihttps://hdl.handle.net/11616/97118
dc.identifier.volume27en_US
dc.identifier.wosWOS:000368728100004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Materials Science-Materials in Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMineral Trioxide Aggregateen_US
dc.subjectPlasma-Mass Spectrometryen_US
dc.subjectPortland-Cementen_US
dc.subjectMetal Contentsen_US
dc.subjectWhite Mtaen_US
dc.subjectBioaggregateen_US
dc.subjectBiodentineen_US
dc.subjectGrayen_US
dc.subjectDifferentiationen_US
dc.subjectBlooden_US
dc.titleDetermination of trace elements in rat organs implanted with endodontic repair materials by ICP-MSen_US
dc.typeArticleen_US

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