Concentrations of trace elements in larynx and skin tissues with epidermoid cancer

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dc.authoridKIZILAY, Ahmet/0000-0003-3048-6489;
dc.authorwosidVural, Hüseyin/B-3300-2016
dc.authorwosidKIZILAY, Ahmet/ABI-8293-2020
dc.authorwosidKALCIOGLU, Mahmut Tayyar/I-5884-2013
dc.authorwosidKalcioglu, M. Tayyar/JAC-1515-2023
dc.contributor.authorKizilay, A
dc.contributor.authorKalcioglu, MT
dc.contributor.authorOzyurt, H
dc.contributor.authorVural, H
dc.contributor.authorSogut, S
dc.contributor.authorCokkeser, Y
dc.contributor.authorAkyol, O
dc.date.accessioned2024-08-04T20:14:43Z
dc.date.available2024-08-04T20:14:43Z
dc.date.issued2004
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground and objectives: Playing a crucial role in a number of biological processes, trace elements are an essential part of the body. Up to now, trace elements-cancer relationships have not had a definitive explanation. This study was scheduled to investigate the trace element content of squamous cell carcinoma of the larynx and skin. Methods: The study was designed as a prospective controlled study. Tissue concentrations of iron, selenium, copper and zinc were studied in 30 patients with squamous cell carcinoma (19 larynx and 11 skin), while 20 tissues (12 larynx and 8 neck) of non-cancerous patients served as control. All samples were taken during surgical operations. Tissue element concentrations were measured by atomic absorption spectrophotometer after tissues were digested in an acid mixture. Results: No meaningful differences were interpreted in copper and zinc in epidermoid cancer and non-cancerous tissues. However, iron and selenium concentrations were found to be decreased significantly in cancer tissues than in control values. Conclusion: Decreased selenium and iron concentrations in the cancerous tissue from the patients with epidermoid cancer may result in increased oxidative stress because of the requirements of these elements for activities of some antioxidant enzymes.en_US
dc.identifier.endpage121en_US
dc.identifier.issn0946-2104
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-1842781108en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage117en_US
dc.identifier.urihttps://hdl.handle.net/11616/93915
dc.identifier.volume21en_US
dc.identifier.wosWOS:000221082300013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherDustri-Verlag Dr Karl Feistleen_US
dc.relation.ispartofTrace Elements and Electrolytesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectsquamous cell carcinomaen_US
dc.subjecttrace elementsen_US
dc.subjectcopperen_US
dc.subjectironen_US
dc.subjectseleniumen_US
dc.subjectzincen_US
dc.subjectlarynxen_US
dc.subjectskinen_US
dc.titleConcentrations of trace elements in larynx and skin tissues with epidermoid canceren_US
dc.typeArticleen_US

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