Therapeutic plasma-exchange in hematologic disease: Results from a single center in Eastern Anatolia

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dc.authoridBERBER, Ilhami/0000-0003-3312-8476
dc.authoridKAYA, Emin/0000-0001-8605-8497
dc.authoridErkurt, Mehmet Ali/0000-0002-3285-417X
dc.authorwosidBERBER, Ilhami/ABI-6231-2020
dc.authorwosidKAYA, Emin/W-2951-2017
dc.authorwosidErkurt, Mehmet Ali/ABI-7232-2020
dc.contributor.authorErkurt, Mehmet Ali
dc.contributor.authorKuku, Lrfan
dc.contributor.authorKaya, Emin
dc.contributor.authorOzgen, Unsal
dc.contributor.authorBerber, Ilhami
dc.contributor.authorKoroglu, Mustafa
dc.contributor.authorOzgul, Mustafa
dc.date.accessioned2024-08-04T20:37:38Z
dc.date.available2024-08-04T20:37:38Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTherapeutic plasma-exchange (TPE) is used as primary and adjunctive therapy in treatment of several hematologic diseases. We retrospectively evaluated the results of TPE in hematologic diseases during 2008-2012. A total of 301 TPE procedures were performed in 44 patients (19 male and 25 female, with mean age of 50.6 +/- 15 years). Fifteen of 44 patients had thrombotic thrombocytopenic purpura (TTP), 14 patients had HELLP syndrome (Hemolysis Elevated Liver enzymes, Low Platelet count), 10 patients had multiple myeloma-hyperviscosity and the rest five patients had snake bite. Fresh frozen plasma (FFP) was used as replacement fluid. Complete response (CR) was achieved on 13 patients (87%) in primarily TTP. CR was achieved in all other three diseases. Total complications were detected in 8.1% of the TPE procedures. Adverse events (AEs), were seen in 5.4% of all procedures. None of the patients died from any complication. AE occurred in 4% (Grade-I), 1% (Grade-II), and 0.3% (Grade-III) of the procedures. The most common AE were nausea/vomiting, hypotension, pruritus and abdominal pain. TPE is effectively and safely carried out in our center in hematologic diseases. (C) 2013 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.transci.2013.04.012
dc.identifier.endpage339en_US
dc.identifier.issn1473-0502
dc.identifier.issue3en_US
dc.identifier.pmid23619323en_US
dc.identifier.scopus2-s2.0-84878836269en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage335en_US
dc.identifier.urihttps://doi.org/10.1016/j.transci.2013.04.012
dc.identifier.urihttps://hdl.handle.net/11616/96089
dc.identifier.volume48en_US
dc.identifier.wosWOS:000321403400013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofTransfusion and Apheresis Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTherapeutic plasma exchangeen_US
dc.subjectPlasmapheresisen_US
dc.subjectAdverse eventsen_US
dc.titleTherapeutic plasma-exchange in hematologic disease: Results from a single center in Eastern Anatoliaen_US
dc.typeArticleen_US

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