Beneficial effects of chrysin on the reproductive system of adult male rats

Basit Öğe Kaydı
dc.authoridaydin, muhterem/0000-0002-6494-9229
dc.authoridCETIN, Asli/0000-0003-3902-3210
dc.authoridCiftci, Osman/0000-0001-5755-3560
dc.authorwosidÖzdemir, İlknur/AAA-6216-2021
dc.authorwosidaydin, muhterem/W-4192-2018
dc.contributor.authorCiftci, O.
dc.contributor.authorOzdemir, I.
dc.contributor.authorAydin, M.
dc.contributor.authorBeytur, A.
dc.date.accessioned2024-08-04T20:35:52Z
dc.date.available2024-08-04T20:35:52Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, the beneficial effect of chrysin, a natural flavonoid currently under investigation due to its important biological activities, on reproductive system of rats was investigated. Rats (n = 16) were divided randomly into two equal groups. Rats in control group were given corn oil as carrier. Chrysin was orally administered at the dose of 50 mg kg-1 per day by gavages, and it was dissolved in corn oil for 60 days. Tissue thiobarbituric acid reactive substances (TBARS) and glutathione (GSH) levels, antioxidant enzyme activity (CAT, SOD and GSH-Px), sperm parameters (motility, concentration and abnormal sperm rate), reproductive organ weight (testes, epididymis, vesicula seminalis, prostate) and serum testosterone levels were determined in the rats. Our results indicated that chrysin significantly increased GSH, CAT, GSH-Px and CuZn-SOD levels, but did not change the formation of TBARS significantly. In addition, sperm motility, sperm concentration and serum testosterone levels significantly increased, whereas abnormal sperm rate significantly decreased with chrysin treatment. In conclusion, it is suggested that treatment with chrysin can positively affect the reproductive system in rats, and it can be used for the treatment of male infertility.en_US
dc.description.sponsorshipIUBAP (Inonu University) [2009/24]en_US
dc.description.sponsorshipWe acknowledge the support of IUBAP (Scientific Research Fund of Inonu University) under Grant 2009/24.en_US
dc.identifier.doi10.1111/j.1439-0272.2010.01127.x
dc.identifier.endpage186en_US
dc.identifier.issn0303-4569
dc.identifier.issn1439-0272
dc.identifier.issue3en_US
dc.identifier.pmid21486424en_US
dc.identifier.scopus2-s2.0-84860245676en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage181en_US
dc.identifier.urihttps://doi.org/10.1111/j.1439-0272.2010.01127.x
dc.identifier.urihttps://hdl.handle.net/11616/95640
dc.identifier.volume44en_US
dc.identifier.wosWOS:000303118500007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAndrologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChrysinen_US
dc.subjectreproductive systemen_US
dc.subjectsperm qualityen_US
dc.subjecttestosteroneen_US
dc.titleBeneficial effects of chrysin on the reproductive system of adult male ratsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu