Prediction of adverse outcome associated with vaginal misoprostol for labor induction

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dc.authoridHaberal, Ali/0000-0002-1486-7209
dc.authorwosidCaliskan, Eray/HTR-8541-2023
dc.authorwosidHaberal, Ali/AAI-9331-2021
dc.contributor.authorMeydanli, MM
dc.contributor.authorCaliskan, E
dc.contributor.authorHaberal, A
dc.date.accessioned2024-08-04T20:13:23Z
dc.date.available2024-08-04T20:13:23Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To identify predictors of adverse outcome in pregnant women at term receiving 50 mug of intravaginal misoprostol for labor induction. Study design: A prospective observational study was conducted of 720 pregnant women at term with an unfavorable cervix and a medical or obstetric indication for labor induction. All patients received 50 mug of intravaginal misoprostol every 4 h up to three doses. The primary outcome measure was adverse outcome defined as: neonatal death, fetal acidemia and emergent cesarean delivery performed for non-reassuring fetal heart rate tracings. A stepwise logistic regression analysis was used to identify predictors of adverse outcome. Results: Tachysystole (frequent uterine contractions) (odds ratio (OR), 3.7; 95% confidence interval (CI), 1.2-10.8) and fetal tachycardia (OR, 4.8; 95% CI, 1.4-16.2) were determined as significant predictors of adverse outcome. The specificity of the model was 94.2%, whereas the sensitivity was 20.4%. Conclusion: In the absence of tachysystole and fetal tachycardia, an uneventful delivery might be expected for women receiving 50 mug of intravaginal misoprostol. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/S0301-2115(03)00105-2
dc.identifier.endpage148en_US
dc.identifier.issn0301-2115
dc.identifier.issn1872-7654
dc.identifier.issue2en_US
dc.identifier.pmid12969573en_US
dc.identifier.scopus2-s2.0-0041825746en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage143en_US
dc.identifier.urihttps://doi.org/10.1016/S0301-2115(03)00105-2
dc.identifier.urihttps://hdl.handle.net/11616/93587
dc.identifier.volume110en_US
dc.identifier.wosWOS:000185509200004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofEuropean Journal of Obstetrics & Gynecology and Reproductive Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmisoprostolen_US
dc.subjectlabor inductionen_US
dc.subjectadverse outcomeen_US
dc.titlePrediction of adverse outcome associated with vaginal misoprostol for labor inductionen_US
dc.typeArticleen_US

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