Effect of CO2 laser on spinal epidural fibrosis

dc.authoridAYDIN, Nasuhi/0000-0003-3145-2432
dc.authorwosidAYDIN, Nasuhi Engin/L-1607-2019
dc.authorwosidAydin, Nasuhi E/B-6536-2012
dc.authorwosidAYDIN, Nasuhi/O-9043-2016
dc.contributor.authorColak, A
dc.contributor.authorBavbek, M
dc.contributor.authorAydin, NE
dc.contributor.authorRenda, N
dc.contributor.authorAcikgoz, B
dc.date.accessioned2024-08-04T20:11:50Z
dc.date.available2024-08-04T20:11:50Z
dc.date.issued1996
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study the effect of CO2 laser on spinal epidural fibrosis was examined in 24 guinea pigs which were divided into two groups. The first group was the control group, the second one the CO2 laser group. All animals had laminectomies at 3 levels. Re-exploration was performed three months after the laminectomy. In the second group the same procedure was performed but at the end of the re-exploration, CO2 laser irradiation of the epidural fibrotic tissue was done. The wounds in both groups were closed again. Four months later all animals were sacrificed. for verification and quantification of scar formation (postoperative fibrosis) light microscopic examinations and determination of hydroxyproline were done, using Bergman's spectrophotometric method. The differences which were observed between the two groups were statistically significant (U:134, p < 0.05). This study demonstrates the reducing effect of CO2 laser irradiation on epidural scar formation. The findings encourage its use as an alternative method of prevention of epidural fibrosis after spinal surgery.en_US
dc.identifier.doi10.1007/BF01411355
dc.identifier.endpage166en_US
dc.identifier.issn0001-6268
dc.identifier.issue2en_US
dc.identifier.pmid8686539en_US
dc.identifier.scopus2-s2.0-0029693727en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage162en_US
dc.identifier.urihttps://doi.org/10.1007/BF01411355
dc.identifier.urihttps://hdl.handle.net/11616/93022
dc.identifier.volume138en_US
dc.identifier.wosWOS:A1996TX18900007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer-Verlag Wienen_US
dc.relation.ispartofActa Neurochirurgicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCO2 laseren_US
dc.subjectepidural fibrosisen_US
dc.subjectpostlaminectomy scaren_US
dc.subject5-hydroxyprolineen_US
dc.titleEffect of CO2 laser on spinal epidural fibrosisen_US
dc.typeArticleen_US

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