A Case of Brucellosis Misdiagnosed as Crimean-Congo Hemorrhagic Fever

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dc.authoridAlmis, Habip/0000-0001-9327-4876
dc.authoridYakıncı, Mehmet Cengiz/0000-0001-5930-4269;
dc.authorwosidAlmis, Habip/AER-7897-2022
dc.authorwosidYakıncı, Mehmet Cengiz/ABI-7519-2020
dc.authorwosidAlmis, Habip/AAD-8730-2022
dc.contributor.authorAlmis, Habip
dc.contributor.authorYakinci, Cengiz
dc.date.accessioned2024-08-04T20:36:10Z
dc.date.available2024-08-04T20:36:10Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBrucellosis which is a zoonotic infection, is an important public health problem in Turkey and all over the world. The disease may involve many organs and systems. Since the symptoms of brucellosis are non-specific, difficulties in differential diagnosis and misdiagnosis are frequent. In this case report we present a case of brucellosis, misdiagnosed as Crimean-Congo hemorrhagic fever (CCHF). A 13-year-old boy was referred from another medical center with preliminary diagnosis of CCHF and admitted to our clinic with fever and a history of presence of a tick on his back. His physical observation only included splenomegaly. The laboratory results on admission were anemia, thrombocytopenia, elevation of acute phase reactants and liver transaminase levels. Abdominal ultrasonography revealed splenomegaly. Since the patient had anemia, epistaxis, fever and thrombocytopenia, he was initially diagnosed as CCHF. Meantime serum sample of the patient had been sent to Refik Saydam National Public Health Agency for CC-IF PCR test. The fever of the patient could not be controlled. His detailed medical history revealed stockbreeding and consumption of raw milk products. Patient's signs and symptoms were also compatible with brucellosis and standard tube agglutination test for brucellosis was positive at 1/1280 titer in serum. The patient was diagnosed as brucellosis and the treatment was started with combination of rifampicin (1 x 600 mg/day) and doxycycline (2 x 100 mg/day). Blood cultures yielded negative result. The PCR tests for CCHF was found also negative. His fever and other complaints improved with treatment which was completed in six weeks and the follow-up was without complications. Turkey is endemic both for brucellosis and CCHF. This case was reported to emphasize that the cases of brucellosis could mimic other diseases and brucellosis should also be considered in the differential diagnosis of CCHF.en_US
dc.identifier.endpage479en_US
dc.identifier.issn0374-9096
dc.identifier.issue3en_US
dc.identifier.pmid22951660en_US
dc.identifier.scopus2-s2.0-84866127955en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage475en_US
dc.identifier.urihttps://hdl.handle.net/11616/95798
dc.identifier.volume46en_US
dc.identifier.wosWOS:000308115400015en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherAnkara Microbiology Socen_US
dc.relation.ispartofMikrobiyoloji Bultenien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBrucellosisen_US
dc.subjectCrimean-Congo hemorrhagic feveren_US
dc.subjectanemiaen_US
dc.subjectthrombocytopeniaen_US
dc.subjectdifferential diagnosisen_US
dc.titleA Case of Brucellosis Misdiagnosed as Crimean-Congo Hemorrhagic Feveren_US
dc.typeArticleen_US

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