Increased mean platelet volume in cervicocephalic artery dissections

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dc.authoridKamisli, Suat/0000-0003-4281-3301
dc.authoridKamisli, Ozden/0000-0003-1114-7860
dc.authoridKamisli, Ozden/0000-0003-1114-7860
dc.authoridozcan, abdulcemal/0000-0002-6759-7556
dc.authorwosidKamisli, Suat/AAC-2706-2021
dc.authorwosidKamisli, Suat/JZT-8388-2024
dc.authorwosidKamisli, Ozden/JVZ-0145-2024
dc.authorwosidKamisli, Suat/JVN-4663-2024
dc.authorwosidKamisli, Ozden/AAA-6553-2020
dc.authorwosidozcan, abdulcemal/B-1348-2008
dc.contributor.authorKamisli, O.
dc.contributor.authorKamisli, S.
dc.contributor.authorGonullu, S.
dc.contributor.authorKaplan, Y.
dc.contributor.authorOzcan, C.
dc.date.accessioned2024-08-04T20:36:10Z
dc.date.available2024-08-04T20:36:10Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractWe aimed to investigate the role of platelets in the pathogenesis of cervicocephalic artery dissections by measuring the mean platelet volume (MPV) and platelet count. Thirty-four patients with evidence of cervicocephalic artery dissection were included in the study. Cervicocephalic artery dissection patients were divided into two subgroups as vertebral artery dissections and carotid artery dissections. There were 30 control subjects with similar baseline characteristics. The platelet count and MPV were compared between groups. The analysis showed a significant difference between the MPV values of the cervicocephalic artery dissection group and the control group (p < 0.05). However, when we compared subgroups with controls, we found a significantly higher MPV values only in the vertebral artery dissection group. We did not find any significant difference for total platelet count between the cervicocephalic artery dissection groups and controls. MPV is a marker of platelet function and activation. Increased MPV may be a result of dissection. In addition, it may be a risk factor for dissection-related stroke. Our study supports the notion that platelet reactivity is important in the pathogenesis of the cervicocephalic artery dissections, especially in vertebral artery dissections.en_US
dc.identifier.doi10.1007/s11845-012-0820-y
dc.identifier.endpage565en_US
dc.identifier.issn0021-1265
dc.identifier.issn1863-4362
dc.identifier.issue4en_US
dc.identifier.pmid22487735en_US
dc.identifier.scopus2-s2.0-84867840195en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage561en_US
dc.identifier.urihttps://doi.org/10.1007/s11845-012-0820-y
dc.identifier.urihttps://hdl.handle.net/11616/95825
dc.identifier.volume181en_US
dc.identifier.wosWOS:000310230000018en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer London Ltden_US
dc.relation.ispartofIrish Journal of Medical Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMean platelet volumeen_US
dc.subjectStrokeen_US
dc.subjectCervicocephalic artery dissectionen_US
dc.subjectPlateletsen_US
dc.titleIncreased mean platelet volume in cervicocephalic artery dissectionsen_US
dc.typeArticleen_US

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