Incidental cancer in colectomy specimens from patients with familial adenomatous polyposis: single centre experience and literature review

Basit Öğe Kaydı
dc.authoridSumer, Fatih/0000-0002-0557-1369
dc.authoridGÜNDOĞDU, RAMAZAN/0000-0002-8799-3265
dc.authoridUylas, Ufuk/0000-0003-4195-5498
dc.authoridTurkmen, Samdanci, Emine/0000-0002-0034-5186
dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authorwosidSumer, Fatih/F-8042-2017
dc.authorwosidGÜNDOĞDU, RAMAZAN/AAJ-5519-2021
dc.authorwosidUylas, Ufuk/A-1827-2019
dc.authorwosidTurkmen, Samdanci, Emine/ABH-4716-2020
dc.contributor.authorUylas, Ufuk
dc.contributor.authorGundogdu, Ramazan
dc.contributor.authorSumer, Fatih
dc.contributor.authorSamdanci, Emine
dc.contributor.authorKayaalp, Cuneyt
dc.date.accessioned2024-08-04T20:53:32Z
dc.date.available2024-08-04T20:53:32Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackgroundSince cancer development is inevitable in patients with familial adenomatous polyposis (FAP), we aimed to determine the incidence of incidental malignancy in prophylactic colectomy specimens.MethodsThe files of patients who underwent prophylactic surgery for FAP between 2010 and 2020 were retrospectively reviewed. The incidence of incidental malignancy in histopathological specimens was examined and a comprehensive literature review was made.ResultsFifty-five patients were included in the study, of whom 30 patients had a diagnosis of primary malignancy. Prophylactic colectomy was performed on 25 patients. The pathology results indicated that the specimens were benign in 12 patients (48%) and revealed carcinoma in situ in 11 patients (44%). Incidental malignancy was detected in 2 patients (8%). In the literature review, there were 243 patients who underwent prophylactic colectomy and incidental cancer was detected in 25 patients (10.3%) with the stages of 1 (7.4%), 2 (2.1%), and 3 (0.8%), respectively.ConclusionsIncidental cancer is not rare in patients who have undergone prophylactic colectomy for FAP. Hopefully. they are usually at early stages and unexpected advanced cancers are seen rarely.en_US
dc.identifier.doi10.1007/s00384-023-04370-4
dc.identifier.issn0179-1958
dc.identifier.issn1432-1262
dc.identifier.issue1en_US
dc.identifier.pmid36949302en_US
dc.identifier.scopus2-s2.0-85150821559en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1007/s00384-023-04370-4
dc.identifier.urihttps://hdl.handle.net/11616/101245
dc.identifier.volume38en_US
dc.identifier.wosWOS:000954748400001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Journal of Colorectal Diseaseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFamilial adenomatous polyposisen_US
dc.subjectColectomyen_US
dc.subjectRectumen_US
dc.subjectCanceren_US
dc.subjectAdenomaen_US
dc.titleIncidental cancer in colectomy specimens from patients with familial adenomatous polyposis: single centre experience and literature reviewen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu