The role of National Institutes of Health category IV prostatitis in accurately staging the newly diagnosed prostate cancer
Küçük Resim Yok
Tarih
2013
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer London Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
It has been known that the National Institutes of Health category IV (NIH-IV) prostatitis increases the serum total prostate-specific antigen (tPSA) in patients with benign prostatic hyperplasia. However, the effect of NIH-IV prostatitis on tPSA levels, which are used for staging prostate cancer (PCa) in patients with PCa, has not been previously investigated. To evaluate the effect of NIH-IV prostatitis on the tPSA which is used for staging PCa in patients with newly diagnosed PCa. A total of 198 patients in whom PCa was detected were included in the study. Group 1 included patients with only PCa, while Group 2 included patients with prostatitis and PCa. The tPSA levels of patients in Groups 1 and 2 were compared. A total of 120 (61 %) PCa (Group 1) and 78 (39 %) PCa + NIH-IV prostatitis (Group 2) patients were identified. The tPSA levels of 70 (58 %) patients in Group 1 and 22 (28 %) patients in Group 2 were at the interval of < 20 ng/ml (the mean levels of tPSA: 11.8 +/- A 4.5 and 14.1 +/- A 3.3, respectively). The tPSA levels of 50 (42 %) patients in Group 1 and 56 (72 %) patients in Group 2 were within the range of a parts per thousand yen20 ng/ml (the mean levels of tPSA: 39.9 +/- A 31.0 and 47.0 +/- A 29.2, respectively). Within both the < 20 ng/ml range and a parts per thousand yen20 ng/ml range, the mean tPSA value in Group 2 was found to be significantly higher than that of Group 1 (p = 0.03 and 0.01, respectively). The existence of NIH-IV prostatitis together with cancer in patients with PCa significantly increases the tPSA level which is used in staging the PCa.
Açıklama
Anahtar Kelimeler
Prostate cancer, Prostate-specific antigen, Prostatitis, Stage, Treatment, Biopsy
Kaynak
Irish Journal of Medical Science
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
182
Sayı
3
