Two possible cases of Trichosporon infections in bone-marrow-transplanted children: The first case of T. japonicum isolated from clinical specimens

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dc.authorscopusid6506426468
dc.authorscopusid57217333809
dc.authorscopusid56635224300
dc.authorscopusid6602612326
dc.authorscopusid24177520800
dc.authorscopusid6603868744
dc.authorscopusid57195695569
dc.contributor.authorA?irbaşli H.
dc.contributor.authorBilgen H.
dc.contributor.authorÖzcan S.K.
dc.contributor.authorOtlu B.
dc.contributor.authorSinik G.
dc.contributor.authorÇerikçio?lu N.
dc.contributor.authorDurmaz R.
dc.date.accessioned2024-08-04T20:02:20Z
dc.date.available2024-08-04T20:02:20Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTrichosporon spp. are emerging as opportunistic agents that cause systemic diseases in immuno-compromised hosts. Trichosporonosis carries a poor prognosis in neutropenic patients. Trichosporon japonicum was isolated from the air and named by Sugita et al. Here we present the first case of T.japonicum isolated from a clinical specimen. Two cases of acute myeloid leukemia who had Trichosporon isolates are discussed because of their rarity and growing importance. T. asahii was isolated from the throat, feces and urine of the first patient. T.japonicum was isolated from the sputum of the second patient. Both cases produced high MICs to itraconazole, and low IMCs to fluconazole and voriconazole. In virulance factor investigations there was (++) biofilm formation in T.japonicum but not in T. asahii. Conventional mycological studies were not adequate for the identification of the isolate at the species level. In our second case as in the first one, the isolate was identified as T. asahii with 99.9% accuracy by API 20C AUX Although two T. asahii isolates from the same patient yielded identical typing profiles by arbitrary primed-MR, the isolates of the two different patients showed different arbitrary primed-PCR typing profiles. However, the genetic identification of the other patient's strain gave the result of T.japonicum.en_US
dc.identifier.endpage132en_US
dc.identifier.issn1344-6304
dc.identifier.issue2en_US
dc.identifier.pmid18362402en_US
dc.identifier.scopus2-s2.0-43449117782en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage130en_US
dc.identifier.urihttps://hdl.handle.net/11616/91615
dc.identifier.volume61en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofJapanese Journal of Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectamphotericin B lipid complexen_US
dc.subjectantibiotic agenten_US
dc.subjectfluconazoleen_US
dc.subjectitraconazoleen_US
dc.subjectvirulence factoren_US
dc.subjectvoriconazoleen_US
dc.subjectacute granulocytic leukemiaen_US
dc.subjectarticleen_US
dc.subjectbiofilmen_US
dc.subjectbone marrow transplantationen_US
dc.subjectcase reporten_US
dc.subjectchilden_US
dc.subjectfeces analysisen_US
dc.subjectfemaleen_US
dc.subjectfungal strainen_US
dc.subjectfungus identificationen_US
dc.subjectfungus isolationen_US
dc.subjectgenetic identificationen_US
dc.subjecthumanen_US
dc.subjectmaleen_US
dc.subjectminimum inhibitory concentrationen_US
dc.subjectmycosisen_US
dc.subjectnucleotide sequenceen_US
dc.subjectopportunistic infectionen_US
dc.subjectpolymerase chain reactionen_US
dc.subjectsputum analysisen_US
dc.subjectsystemic diseaseen_US
dc.subjectthroat cultureen_US
dc.subjectTrichosporonen_US
dc.subjectTrichosporon asahiien_US
dc.subjectTrichosporon japonicumen_US
dc.subjecturinalysisen_US
dc.subjectAntibiotics, Antineoplasticen_US
dc.subjectAntifungal Agentsen_US
dc.subjectBone Marrow Transplantationen_US
dc.subjectChilden_US
dc.subjectFatal Outcomeen_US
dc.subjectFemaleen_US
dc.subjectHumansen_US
dc.subjectIdarubicinen_US
dc.subjectImmunocompromised Hosten_US
dc.subjectInfanten_US
dc.subjectItraconazoleen_US
dc.subjectLeukemia, Myeloid, Acuteen_US
dc.subjectMaleen_US
dc.subjectMycosesen_US
dc.subjectNeutropeniaen_US
dc.subjectOpportunistic Infectionsen_US
dc.subjectPolymerase Chain Reactionen_US
dc.subjectTrichosporonen_US
dc.titleTwo possible cases of Trichosporon infections in bone-marrow-transplanted children: The first case of T. japonicum isolated from clinical specimensen_US
dc.typeArticleen_US

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