Malondıaldehyde glutathıone and nıtrıc oxıde levels ın patıents wıthenterobıus vermıcularıs ınfectıon

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dc.contributor.authorKıran, Tuğba Raika
dc.contributor.authorKaraman, Ülkü
dc.contributor.authorÇolak, Cemil
dc.contributor.authorKarabulut, Aysun Bay
dc.contributor.authorDaldal, Nilgün
dc.date.accessioned2018-01-16T12:14:30Z
dc.date.available2018-01-16T12:14:30Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.descriptionMikrobiyol Bul. 2010 Jan;44(1):165-7.en_US
dc.description.abstractThe aim of this study was to investigate the levels of malondialdehyde (MDA) and nitric oxide (NO) which are indicators of oxidative stress and also the level of glutathione (GSH) which is an antioxidant molecule, in patients with Enterobius vermicularis infection. A total of 41 patients (mean age: 36.4 years; 31 were male) and 40 healthy controls (mean age: 40.2 years; 28 were male) were included to the study. None of the patients and controls have had history of hormone/steroid drug use, smoking and alcoholism. The mean level of GSH in patient and control groups were found 1.17 +/- 0.02 micromol/l and 2.49 +/- 0.10 micromol/l; MDA 26.97 +/- 2.06 micromol/l and 19.47 +/- 2.25 micromol/l; NO 20.74 +/- 0.60 micromol/dl and 17.83 +/- 0.50 micromol/dl, respectively. The mean GSH level in patient group was statistically significantly lower (p < 0.05) than controls, while the mean MDA and NO levels were statistically significantly higher (p < 0.05). These results indicated that the consumption of GSH was increased due to the severity of oxidative stress in patients infected with E. vermicularis. Detailed experimental and clinical studies are required to enlighten the relation of GSH in the pathogenesis of E. vermicularis infection. Since oxidative stress is increased during enterobiosis, the use of antioxidant agents (e.g. vitamins C and E) for the supportive treatment deserves evaluation.en_US
dc.identifier.citationKiran TR, Karaman U, Colak C, Bay Karabulut A, Daldal N. (2010).en_US
dc.identifier.endpage167en_US
dc.identifier.issue1en_US
dc.identifier.startpage165en_US
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pubmed/20455415
dc.identifier.urihttps://hdl.handle.net/11616/7988
dc.identifier.volume44en_US
dc.language.isoenen_US
dc.publisherMikrobiyol Bul. 2010 Jan;44(1):165-7.en_US
dc.relation.ispartofMikrobiyol Bul. 2010 Jan;44(1):165-7.en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleMalondıaldehyde glutathıone and nıtrıc oxıde levels ın patıents wıthenterobıus vermıcularıs ınfectıonen_US
dc.typeArticleen_US

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