Evaluation of intestinal metaplasia associated with alkaline reflux gastritis and Helicobacter pylori in patients without gastric surgery

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dc.contributor.authorErdoğan, Mehmet Ali
dc.contributor.authorAksakal, Gökhan
dc.date.accessioned2024-08-04T19:42:45Z
dc.date.available2024-08-04T19:42:45Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: Alkaline reflux gastritis is a term used for gastric mucosa damage due to reflux of duodenal and pancreatic content into stomach. In addition to many histopathological changes caused by alkaline reflux gastritis, the relationship of alkaline reflux gastritis with intestinal metaplasia is also important. Gastric intestinal metaplasia is a precancerous lesion that requires a follow-up protocol.Material and Methods: This study included 1005 patients who underwent esophagogastroduodenoscopy and were diagnosed with alkaline reflux gastritis at Endoscopy Unit of Gastroenterology Department of Karabük University, Medical School between January 2013 and January 2016.Results: When the data of these patients were retrospectively reviewed, intestinal metaplasia was detected in 203 patients (20.2%), whereas Helicobacter pylori was detected in 466 patients (46.4%). There was pyloric dysfunction in 359 patients (35.7%) but 646 patients (64.3%) did not have pyloric dysfunction.Conclusion: In our study, it was found that there was an increase in the frequency of intestinal metaplasia in patients with alkaline reflux gastritis who had increased with age, male gender and Helicobacter pylori. This was a retrospective study indicating the association of H. pylori with intestinal metaplasia in patients with alkaline reflux gastritis. We think that there is a need for further prospective studies to investigate the presence of intestinal metaplasia in patients with alkaline reflux gastritisen_US
dc.identifier.doi10.5455/jtomc.2018.02.030
dc.identifier.endpage261en_US
dc.identifier.issn2636-7688
dc.identifier.issue2en_US
dc.identifier.startpage258en_US
dc.identifier.trdizinid285550en_US
dc.identifier.urihttps://doi.org/10.5455/jtomc.2018.02.030
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/285550
dc.identifier.urihttps://hdl.handle.net/11616/88659
dc.identifier.volume25en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of intestinal metaplasia associated with alkaline reflux gastritis and Helicobacter pylori in patients without gastric surgeryen_US
dc.typeArticleen_US

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